Immunity to Experimental Renal Candidiasis in Rats

Overview

Journal Infect Immun

Publisher American Society for Microbiology

Specialty Allergy & Immunology

Date 1978 Feb 1

PMID 344222

Citations 6

Authors

T J Rogers

E Balish

Affiliations

Soon will be listed here.

Abstract

Germfree rats were found to be more susceptible to intravenous challenge with Candida albicans than were conventional rats. The resistance of conventional rats could be overcome by increasing the challenge dose. The resistance of the germfree rat was enhanced by vaccination with Formalin-killed C. albicans in complete Freund adjuvant, complete Freund adjuvant, or incomplete Freund adjuvant. These results, and histological evidence obtained from infected gnotobiotic rats, provided further information on the mechanism of resistance to the disseminated form of candidiasis.

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Immunity to Candida albicans.

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PMID: 7010113 PMC: 373198. DOI: 10.1128/mr.44.4.660-682.1980.

Inoculation candidiasis in a murine model of severe combined immunodeficiency syndrome.

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Characteristics of Candida albicans adherence to mouse tissues.

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Effect of systemic candidiasis on blastogenesis of lymphocytes from germfree and conventional rats.

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PMID: 352927 PMC: 421564. DOI: 10.1128/iai.20.1.142-150.1978.

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