Novel Histone Acetyltransferase (HAT) Inhibitors for Treating Diseases

Overview

Journal ACS Med Chem Lett

Publisher American Chemical Society

Specialty Chemistry

Date 2021 Aug 20

PMID 34413940

Citations 8

Authors

Ram W Sabnis

Affiliations

Soon will be listed here.

Citing Articles

Unlocking the epigenetic code: new insights into triple-negative breast cancer.

Mahendran G, Shangaradas A, Romero-Moreno R, Wickramarachchige Dona N, Sarasija S, Perera S Front Oncol. 2025; 14:1499950.

PMID: 39744000 PMC: 11688480. DOI: 10.3389/fonc.2024.1499950.

Acetylation of Histone H3 in Cancer Progression and Prognosis.

Miziak P, Baran M, Borkiewicz L, Trombik T, Stepulak A Int J Mol Sci. 2024; 25(20).

PMID: 39456765 PMC: 11507103. DOI: 10.3390/ijms252010982.

Post-Translational Modifications of Proteins of Malaria Parasites during the Life Cycle.

Schwarzer E, Skorokhod O Int J Mol Sci. 2024; 25(11).

PMID: 38892332 PMC: 11173270. DOI: 10.3390/ijms25116145.

The pharmacoepigenetic paradigm in cancer treatment.

Ocana-Paredes B, Rivera-Orellana S, Ramirez-Sanchez D, Montalvo-Guerrero J, Freire M, Espinoza-Ferrao S Front Pharmacol. 2024; 15:1381168.

PMID: 38720770 PMC: 11076712. DOI: 10.3389/fphar.2024.1381168.

Epigenetic regulation as a therapeutic target in the malaria parasite Plasmodium falciparum.

Reyser T, Paloque L, Augereau J, Di Stefano L, Benoit-Vical F Malar J. 2024; 23(1):44.

PMID: 38347549 PMC: 10863139. DOI: 10.1186/s12936-024-04855-9.

References

He Z, Wei B, Zhang X, Gong Y, Ma L, Zhao W . Current development of CBP/p300 inhibitors in the last decade. Eur J Med Chem. 2020; 209:112861. DOI: 10.1016/j.ejmech.2020.112861. View

Burns A, Graff J . Cognitive epigenetic priming: leveraging histone acetylation for memory amelioration. Curr Opin Neurobiol. 2020; 67:75-84. DOI: 10.1016/j.conb.2020.08.011. View

Fioravanti R, Mautone N, Rovere A, Rotili D, Mai A . Targeting histone acetylation/deacetylation in parasites: an update (2017-2020). Curr Opin Chem Biol. 2020; 57:65-74. DOI: 10.1016/j.cbpa.2020.05.008. View

Wang Y, Xie Q, Tan H, Liao M, Zhu S, Zheng L . Targeting cancer epigenetic pathways with small-molecule compounds: Therapeutic efficacy and combination therapies. Pharmacol Res. 2021; 173:105702. DOI: 10.1016/j.phrs.2021.105702. View

Gomathi K, Akshaya N, Srinaath N, Rohini M, Selvamurugan N . Histone acetyl transferases and their epigenetic impact on bone remodeling. Int J Biol Macromol. 2020; 170:326-335. DOI: 10.1016/j.ijbiomac.2020.12.173. View