Effect of a Nitrogen Analog of Tetrahydrocannabinol on Cancer Pain

Overview

Journal Clin Pharmacol Ther

Publisher Wiley

Specialty Pharmacology

Date 1978 Apr 1

PMID 343969

Citations 24

Authors

M STAQUET

C Gantt

D Machin

Affiliations

Soon will be listed here.

Abstract

Two consecutive, randomized, double-blind trials were performed to test the analgesic properties of a synthetic nitrogen analog of tetrahydrocannabinol (NIB). In the first trial, the test preparation was superior to placebo and approximately equivalent to 50 mg of codeine phosphate. In the second study, the tetrahydrocannabinol analog was superior to placebo and to 50 mg secobarbital. NIB is not useful clinically because of the frequency of side effects.

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