Neoadjuvant Therapy for Neuroendocrine Neoplasms: Recent Progresses and Future Approaches

Overview

Journal Front Endocrinol (Lausanne)

Specialty Endocrinology

Date 2021 Aug 12

PMID 34381421

Citations 10

Authors

Andrea Lania

Francesco Ferrau

Manila Rubino

Roberta Modica

Annamaria Colao

Antongiulio Faggiano

Affiliations

Soon will be listed here.

Abstract

Neuroendocrine neoplasms (NENs) are a heterogeneous group of tumors, their treatment being challenging and requiring a multidisciplinary approach. Though the only curative treatment is surgery, up to 50% of patients are diagnosed with metastatic disease. In the last years, neoadjuvant chemo(radio)therapy has become part of the standard of care in the treatment of different cancer types. However, evidence of its efficacy and safety in NEN patients has not yet been confirmed in the literature. The aim of the present review is to perform an extensive review of the scientific evidence for neoadjuvant therapy in patients with gastroenteropancreatic and thoracic NENs.

Citing Articles

Gastroenteropancreatic neuroendocrine neoplasms: epidemiology, genetics, and treatment.

Tan B, Zhang B, Chen H Front Endocrinol (Lausanne). 2024; 15:1424839.

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Contemporary Approaches to the Surgical Management of Pancreatic Neuroendocrine Tumors.

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The Hong Kong consensus recommendations on the diagnosis and management of pancreatic cystic lesions.

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Validated Pretreatment Prediction Models for Response to Neoadjuvant Therapy in Patients with Rectal Cancer: A Systematic Review and Critical Appraisal.

Tanaka M, Geubels B, Grotenhuis B, Marijnen C, Peters F, Van der Mierden S Cancers (Basel). 2023; 15(15).

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Psychological distress and resilience in patients with gastroenteropancreatic neuroendocrine tumor.

Song L, Cao Y, Li J, Lu M, Tang L Front Endocrinol (Lausanne). 2022; 13:947998.

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