» Articles » PMID: 34368678

Prospective Review of Testing Indications to Inform Local Laboratory Stewardship Initiatives

Overview
Date 2021 Aug 9
PMID 34368678
Citations 1
Authors
Affiliations
Soon will be listed here.
Abstract

We conducted a prospective chart review to determine the prevalence of and reasons for inappropriate test-ordering at a tertiary care hospital. Inappropriate orders accounted for 54% of all tests. The two primary aetiologies of inappropriate test-ordering were an alternative reason for diarrhoea (34%) and an asymptomatic patient (20%). These results highlight the need to focus diagnostic stewardship of testing on pre-analytical factors.

Citing Articles

Impact of mandatory nucleic acid amplification test (NAAT) testing approval on hospital-onset infection (HO-CDI) rates: A diagnostic stewardship intervention.

McCormick W, Jackson G, Andrea S, Whitehead V, Chargualaf T, Touzard-Romo F Infect Control Hosp Epidemiol. 2023; 45(1):106-109.

PMID: 37424227 PMC: 10782198. DOI: 10.1017/ice.2023.92.

References
1.
Magill S, Edwards J, Bamberg W, Beldavs Z, Dumyati G, Kainer M . Multistate point-prevalence survey of health care-associated infections. N Engl J Med. 2014; 370(13):1198-208. PMC: 4648343. DOI: 10.1056/NEJMoa1306801. View

2.
White D, Hamilton K, Pegues D, Hanish A, Umscheid C . The Impact of a Computerized Clinical Decision Support Tool on Inappropriate Clostridium difficile Testing. Infect Control Hosp Epidemiol. 2017; 38(10):1204-1208. DOI: 10.1017/ice.2017.161. View

3.
Zou J, Leung V, Champagne S, Hinch M, Wong A, Lloyd-Smith E . Clinical heterogeneity of patients with stool samples testing PCR+/Tox- from a two-step Clostridium difficile diagnostic algorithm. Eur J Clin Microbiol Infect Dis. 2018; 37(12):2355-2359. DOI: 10.1007/s10096-018-3383-7. View

4.
Polage C, Gyorke C, Kennedy M, Leslie J, Chin D, Wang S . Overdiagnosis of Clostridium difficile Infection in the Molecular Test Era. JAMA Intern Med. 2015; 175(11):1792-801. PMC: 4948649. DOI: 10.1001/jamainternmed.2015.4114. View

5.
Buckel W, Avdic E, Carroll K, Gunaseelan V, Hadhazy E, Cosgrove S . Gut check: Clostridium difficile testing and treatment in the molecular testing era. Infect Control Hosp Epidemiol. 2015; 36(2):217-21. DOI: 10.1017/ice.2014.19. View