Relationship Between Blood Glucose and Hemoglobin A1c Levels and Urinary Incontinence in Women

Overview

Journal Int J Gen Med

Publisher Dove Medical Press

Specialty General Medicine

Date 2021 Aug 9

PMID 34366679

Citations 3

Authors

Ning Liu

Li Xing

Weipu Mao

Shuqiu Chen

Jianping Wu

Bin Xu

Ming Chen

Affiliations

Soon will be listed here.

Abstract

Objective: The purpose of this study was to evaluate the associations between blood glucose and hemoglobin A1c (HbA1c) levels with the degree of stress urinary incontinence (SUI) and urgency urinary incontinence (UUI) in women.

Methods: We conducted a cross-sectional study of female participants in the National Health and Nutrition Examination Survey (NHANES) database between 2007 and 2012. Univariate and multivariate logistic regressions were used to assess the relationship between blood glucose and HbA1c levels and the degree of SUI and UUI.

Results: A total of 3821 participants were enrolled in the study, of whom 2421 (63.4%) had no SUI, 1133 (29.7%) had monthly SUI, 267 (7.0%) had weekly SUI; 2883 (75.5%) had no UUI, 735 (19.2%) had monthly UUI, 203 (5.3%) had weekly UUI. The levels of blood glucose and HbA1c were positively correlated with SUI and UUI, and increased with increasing degree of UUI. Multivariate logistic regression showed that there was a positive association between blood HbA1c level and degree of SUI.

Conclusion: Our study found that blood glucose and HbA1c levels can be used as indicators of SUI and UUI severity in women.

Citing Articles

Genetic support of causal association between lipid and glucose metabolism and stress urinary incontinence in women: a bidirectional Mendelian randomization and multivariable-adjusted study.

Xiang N, Su S, Yang Y, Luo Y, Fu T, Wang L Front Endocrinol (Lausanne). 2024; 15:1394252.

PMID: 39351534 PMC: 11439682. DOI: 10.3389/fendo.2024.1394252.

An evaluation of lower urinary tract symptoms in diabetic patients: a cross-sectional study.

Qasrawi H, Tabouni M, Almansour S, Ghannam M, Abdalhaq A, Abushamma F BMC Urol. 2022; 22(1):178.

PMID: 36357918 PMC: 9648430. DOI: 10.1186/s12894-022-01133-1.

Potential role of oxidative stress in the pathogenesis of diabetic bladder dysfunction.

Song Q, Sun Y, Deng K, Mei J, Chermansky C, Damaser M Nat Rev Urol. 2022; 19(10):581-596.

PMID: 35974244 DOI: 10.1038/s41585-022-00621-1.

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