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The Fragility Index for Assessing the Robustness of the Statistically Significant Results of Experimental Clinical Studies

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Publisher Springer
Specialty General Medicine
Date 2021 Aug 6
PMID 34357573
Citations 13
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References
1.
Brown J, Lane A, Cooper C, Vassar M . The Results of Randomized Controlled Trials in Emergency Medicine Are Frequently Fragile. Ann Emerg Med. 2018; 73(6):565-576. DOI: 10.1016/j.annemergmed.2018.10.037. View

2.
Narayan V, Gandhi S, Chrouser K, Evaniew N, Dahm P . The fragility of statistically significant findings from randomised controlled trials in the urological literature. BJU Int. 2018; 122(1):160-166. DOI: 10.1111/bju.14210. View

3.
Evaniew N, Files C, Smith C, Bhandari M, Ghert M, Walsh M . The fragility of statistically significant findings from randomized trials in spine surgery: a systematic survey. Spine J. 2015; 15(10):2188-97. DOI: 10.1016/j.spinee.2015.06.004. View

4.
Edwards E, Wayant C, Besas J, Chronister J, Vassar M . How Fragile Are Clinical Trial Outcomes That Support the CHEST Clinical Practice Guidelines for VTE?. Chest. 2018; 154(3):512-520. DOI: 10.1016/j.chest.2018.01.031. View

5.
Noel C, McMullen C, Yao C, Monteiro E, Goldstein D, Eskander A . The fragility of statistically significant findings from randomized trials in head and neck surgery. Laryngoscope. 2018; 128(9):2094-2100. DOI: 10.1002/lary.27183. View