Recent Findings in Azaphilone Pigments

Overview

Journal J Fungi (Basel)

Date 2021 Aug 6

PMID 34356920

Citations 9

Authors

Lucia P S Pimenta

Dhionne C Gomes

Patricia G Cardoso

Jacqueline A Takahashi

Affiliations

Soon will be listed here.

Abstract

Filamentous fungi are known to biosynthesize an extraordinary range of azaphilones pigments with structural diversity and advantages over vegetal-derived colored natural products such agile and simple cultivation in the lab, acceptance of low-cost substrates, speed yield improvement, and ease of downstream processing. Modern genetic engineering allows industrial production, providing pigments with higher thermostability, water-solubility, and promising bioactivities combined with ecological functions. This review, covering the literature from 2020 onwards, focuses on the state-of-the-art of azaphilone dyes, the global market scenario, new compounds isolated in the period with respective biological activities, and biosynthetic pathways. Furthermore, we discussed the innovations of azaphilone cultivation and extraction techniques, as well as in yield improvement and scale-up. Potential applications in the food, cosmetic, pharmaceutical, and textile industries were also explored.

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