A Practical Approach to the Diagnosis and Management of Classic Lichen Planopilaris

Overview

Journal Am J Clin Dermatol

Specialty Dermatology

Date 2021 Aug 4

PMID 34347282

Citations 14

Authors

Katerina Svigos

Lu Yin

Lauren Fried

Kristen Lo Sicco

Jerry Shapiro

Affiliations

Soon will be listed here.

Abstract

Lichen planopilaris is a primary lymphocytic cicatricial alopecia that commonly presents with hair loss at the vertex or parietal scalp. Patients may also have associated scalp itching, burning or tenderness. Due to scarring, hair loss is typically permanent. The main goals of treatment are reducing symptoms and preventing disease progression and further hair loss. Currently, the literature has limited evidence on treatments for this difficult condition, and most available evidence is from case reports and case series. Furthermore, the evidence shows a varied response to therapy, with frequent reports of poor response. This article reviews the diagnosis of this rare disease, summarize the currently available treatments, and provide insights and practices from alopecia experts.

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The role of skin microbiota in lichen planus from a Mendelian randomization perspective.

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Increased expression of psoriasin (S100A7) and interleukin 17 (IL-17) in lesional skin in lichen planopilaris.

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