Occurrence, Distribution and Pattern Analysis of Methicillin Resistant (MRSA) and Methicillin Sensitive (MSSA) Staphylococcus Aureus on Fomites in Public Facilities

Overview

Journal Pathog Glob Health

Specialties Infectious Diseases
Microbiology
Public Health

Date 2021 Aug 2

PMID 34338618

Citations 1

Authors

Ziad W Jaradat

Maysoon Khwaileh

Waseem Al Mousa

Qutaiba O Ababneh

Anas Al Nabulsi

Affiliations

Soon will be listed here.

Abstract

Methicillin-resistant (MRSA) is a human pathogen incriminated as a causative agent of hospital nosocomial infections as well as a wide range of diseases in communities. This study was conducted to assess the occurrence and distribution of MRSA and methicillin-sensitive (MSSA) on different fomites in public facilities in northern Jordan and to determine their antibiograms, toxin genes profiles, as well as identify their genetic relatedness. A total of 2600 swabs were collected from 14 fomite surfaces in a variety of public facilities including hospitals, universities, schools, transportation sites, and market places. The identity of the 380 isolates was confirmed. Among them, 158 (41.6%) were MRSA while the rest of the isolates, 222 (58.4%) were MSSA. MRSA isolates were recovered from all fomites sites. However, among the total collected samples, the percentages of MRSA in public facilities were significantly higher in hospitals and transportation fomites, while percentages of MRSA among fomites sites were higher in public reception sites, chairs, and toilet seats. Antibiotic resistance profiles indicated that 24.5% of the isolates were resistant to cefoxitin, oxacillin, and oxytetracycline. In contrast, only 3.95% were resistant to trimethoprim-sulfamethoxazole, and 15.3% were resistant to ciprofloxacin. Multidrug-resistant patterns were higher in MRSA than in MSSA isolates. There was no apparent difference in toxin gene profiles between MRSA and MSSA. Molecular analysis revealed 85 patterns and 16 clusters at a 9% mean similarity level. In conclusion, this study provides evidence for the potential of MRSA transmission via inanimate surfaces.

Citing Articles

Emergence and Genomic Characterization of a Type t4407 ST6-SCC Type IVa Methicillin-Resistant Strain Isolated from Al-Karak Hospital, Jordan.

Gaber Y, TumAllah H, AbdelAllah N, Al-Zereini W, Abu-Lubad M, Aqel A Medicina (Kaunas). 2024; 60(2).

PMID: 38399582 PMC: 10890080. DOI: 10.3390/medicina60020295.

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