» Articles » PMID: 34307548

Liver Injury in COVID-19: Known and Unknown

Overview
Specialty General Medicine
Date 2021 Jul 26
PMID 34307548
Citations 8
Authors
Affiliations
Soon will be listed here.
Abstract

Since the first report of the coronavirus disease 2019 (COVID-19) in December 2019 in Wuhan, China, the outbreak of the disease is currently continuously evolving. Previous studies have shown varying degrees of liver damage in patients with COVID-19. However, the exact causes of liver injury and the relationship between COVID-19 and liver injury is unclear. This article describes liver injury induced by COVID-19, analyzes its causes, and discusses the treatment and prognosis of liver damage in patients with COVID-19.

Citing Articles

Insight into COVID-19 associated liver injury: Mechanisms, evaluation, and clinical implications.

Nasir N, Khanum I, Habib K, Wagley A, Arshad A, Majeed A Hepatol Forum. 2024; 5(3):139-149.

PMID: 39006140 PMC: 11237249. DOI: 10.14744/hf.2023.2023.0025.


The Role of APRI, FIB-4, and SAD-60 Scores as Predictors of Mortality in COVID-19 Patients.

Copur B, Surme S, Tuncer G, Bayramlar O Infect Dis Clin Microbiol. 2024; 5(2):144-152.

PMID: 38633008 PMC: 10985813. DOI: 10.36519/idcm.2023.233.


NASH/NAFLD-Related Hepatocellular Carcinoma: An Added Burden.

Georgescu D, Lighezan D, Rosca C, Nistor D, Ancusa O, Suceava I Life (Basel). 2024; 14(1).

PMID: 38255641 PMC: 10817629. DOI: 10.3390/life14010025.


Investigating Acute Hepatitis after SARS-CoV-2 Vaccination or Infection: A Genetic Case Series.

Bernasconi E, Biagi M, Di Agostino S, Cursaro C, Felicani C, Ronconi E Biomedicines. 2023; 11(10).

PMID: 37893221 PMC: 10604753. DOI: 10.3390/biomedicines11102848.


Evaluation of Curcumin-Piperine Supplementation in COVID-19 Patients Admitted to the Intensive Care: A Double-Blind, Randomized Controlled Trial.

Askari G, Bagherniya M, Kiani Z, Alikiaii B, Mirjalili M, Shojaei M Adv Exp Med Biol. 2023; 1412:413-426.

PMID: 37378780 DOI: 10.1007/978-3-031-28012-2_22.


References
1.
Arentz M, Yim E, Klaff L, Lokhandwala S, Riedo F, Chong M . Characteristics and Outcomes of 21 Critically Ill Patients With COVID-19 in Washington State. JAMA. 2020; 323(16):1612-1614. PMC: 7082763. DOI: 10.1001/jama.2020.4326. View

2.
Jiang S, Wang R, Li L, Hong D, Ru R, Rao Y . Liver Injury in Critically Ill and Non-critically Ill COVID-19 Patients: A Multicenter, Retrospective, Observational Study. Front Med (Lausanne). 2020; 7:347. PMC: 7324794. DOI: 10.3389/fmed.2020.00347. View

3.
Lei F, Liu Y, Zhou F, Qin J, Zhang P, Zhu L . Longitudinal Association Between Markers of Liver Injury and Mortality in COVID-19 in China. Hepatology. 2020; 72(2):389-398. PMC: 7267515. DOI: 10.1002/hep.31301. View

4.
Mishra K, Naffouj S, Gorgis S, Ibrahim H, Gill S, Fadel R . Liver Injury as a Surrogate for Inflammation and Predictor of Outcomes in COVID-19. Hepatol Commun. 2021; 5(1):24-32. PMC: 7789831. DOI: 10.1002/hep4.1586. View

5.
Bashash D, Olfatifar M, Hadaegh F, Aghdaei H, Zali M . COVID-19 prognosis: what we know of the significance and prognostic value of liver-related laboratory parameters in SARS-CoV-2 infection. Gastroenterol Hepatol Bed Bench. 2020; 13(4):313-320. PMC: 7682969. View