» Articles » PMID: 34306911

Dural Venous Sinus Thrombosis After Vestibular Schwannoma Surgery: The Anticoagulation Dilemma

Overview
Publisher Thieme
Date 2021 Jul 26
PMID 34306911
Citations 4
Authors
Affiliations
Soon will be listed here.
Abstract

 Dural venous sinus thrombosis (DVST) is a relatively understudied complication of vestibular schwannoma (VS) surgery. Several studies have examined this topic; however, there is limited data on the incidence, clinical progression, and proper management of this patient population.  A retrospective review was performed for patients undergoing surgery for VS at a single institution. All postoperative imaging was reviewed for incidence of DVST. Demographic data were collected including tumor and surgical characteristics along with postoperative course.  A total of 63 patients underwent resection of their VS. The incidence of DVST was 34.9%. The operative time was greater in the dural venous sinus thrombosis (DSVT) group, at an average of 6.69 hours versus 4.87 in the no DSVT cohort (  = 0.04). Tumor size was correlationally significant (  = 0.051) at 2.75 versus 2.12 cm greatest diameter. The translabyrinthine approach was most prevalent (68.2%). The side of the thrombosis was ipsilateral to the tumor and surgery in all patients. The sigmoid sinus was most commonly involved (95.5%). Of them, 85% patients had a codominant or thrombus contralateral to the dominant sinus. All patients were asymptomatic. No patients were treated with anticoagulation. Resolution of thrombus was seen in five (22.7%) of the patients on last follow-up imaging. There were no hemorrhagic complications.  The overall incidence of DVST was (34.9%) of 63 patients who underwent VS surgery. All patients were asymptomatic and none were treated with anticoagulation. In our study, continuing to observe asymptomatic patients did not lead to any adverse events.

Citing Articles

Iatrogenic intracranial venous hypertension treated with intracranial venous stenting: illustrative case.

Snyder M, Heilman C, Malek A J Neurosurg Case Lessons. 2025; 9(10).

PMID: 40063991 PMC: 11894280. DOI: 10.3171/CASE24781.


Evaluating the effectiveness and complications of the Retrosigmoid, Translabyrinthine and Middle Fossa approaches in vestibular Schwannoma surgical management: a comprehensive systematic review and meta-analysis of 6,889 patients.

Garcia-Torrico F, Mendieta C, Vasconcellos F, Vargas V, Scalise M, Mamani-Julian K Neurosurg Rev. 2025; 48(1):229.

PMID: 39930308 DOI: 10.1007/s10143-025-03237-2.


Prevalence and patterns of cerebral venous sinus thrombosis following vestibular schwannoma surgery: a systematic review and meta-analysis.

Mirdamadi A, Javid M, Nemati S, Keivanlou M, Javid M, Amini-Salehi E Eur Arch Otorhinolaryngol. 2024; 281(8):3879-3891.

PMID: 38443628 DOI: 10.1007/s00405-024-08534-y.


Post-operative segmental cerebral venous sinus thrombosis: risk factors, clinical implications, and therapeutic considerations.

Sturiale C, Auricchio A, Valente I, Vacca A, Pennisi G, Ciaffi G Neurosurg Rev. 2023; 46(1):161.

PMID: 37395915 PMC: 10317877. DOI: 10.1007/s10143-023-02067-4.


Management of jugular bulb injury during retrosigmoid transmeatal resection of vestibular schwannoma.

Constanzo F, de Almeida Teixeira B, Neto M, Ramina R Neurosurg Focus Video. 2022; 5(2):V5.

PMID: 36285237 PMC: 9550010. DOI: 10.3171/2021.7.FOCVID2155.


References
1.
Sade B, Mohr G, Dufour J . Vascular complications of vestibular schwannoma surgery: a comparison of the suboccipital retrosigmoid and translabyrinthine approaches. J Neurosurg. 2007; 105(2):200-4. DOI: 10.3171/jns.2006.105.2.200. View

2.
Ohata K, Haque M, Morino M, Nagai K, Nishio A, Nishijima Y . Occlusion of the sigmoid sinus after surgery via the presigmoidal-transpetrosal approach. J Neurosurg. 1998; 89(4):575-84. DOI: 10.3171/jns.1998.89.4.0575. View

3.
Sari S, Verim S, Hamcan S, Battal B, Akgun V, Akgun H . MRI diagnosis of dural sinus - Cortical venous thrombosis: Immediate post-contrast 3D GRE T1-weighted imaging versus unenhanced MR venography and conventional MR sequences. Clin Neurol Neurosurg. 2015; 134:44-54. DOI: 10.1016/j.clineuro.2015.04.013. View

4.
Ferro J, Canhao P . Cerebral venous sinus thrombosis: update on diagnosis and management. Curr Cardiol Rep. 2014; 16(9):523. DOI: 10.1007/s11886-014-0523-2. View

5.
Benjamin C, Sen R, Golfinos J, Sen C, Roland J, McMenomey S . Postoperative cerebral venous sinus thrombosis in the setting of surgery adjacent to the major dural venous sinuses. J Neurosurg. 2018; 131(4):1317-1323. DOI: 10.3171/2018.4.JNS18308. View