Atypical Thyroid Function Tests and Thyroid Hormone Resistance

Overview

Journal Cureus

Specialty Biomedical Engineering

Date 2021 Jul 26

PMID 34306893

Citations 1

Authors

Vishwanath Pattan

Ishita Mehra

Syed Anjum Khan

Rahul Kashyap

Affiliations

Soon will be listed here.

Abstract

Clinical interpretation of thyroid labs is usually straightforward. However, there are rare instances when the atypical profile of thyroid labs warrants systematic investigation to determine the underlying cause. We report the case of a 90-year-old Caucasian male with a chronic history of atrial fibrillation with chronic pacemaker dependence who presented with significantly elevated free thyroxine level (>7.77 ng/dL) but normal thyroid-stimulating hormone level (2.15 µIU/mL). After ruling out pituitary tumors and artifactual errors due to lab interference, the diagnosis of thyroid hormone resistance was made.

Citing Articles

R243W Mutation in Thyroid Hormone Resistance Syndrome Beta: A Case Report.

Ong J, W Omar W, Tuan Ismail T, Chatterjee K, Hussain S J ASEAN Fed Endocr Soc. 2024; 39(2):81-85.

PMID: 39620185 PMC: 11604371. DOI: 10.15605/jafes.039.02.04.

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