Candida Chorioamnionitis in Mothers with Gestational Diabetes Mellitus: A Report of Two Cases

Overview

Journal Int J Environ Res Public Health

Publisher MDPI

Specialties Environmental Health
Public Health

Date 2021 Jul 24

PMID 34299901

Citations 5

Authors

Elia Shazniza Shaaya

Siti Atiqah Abdul Halim

Ka Wen Leong

Kevin Boon Ping Ku

Pei Shan Lim

Geok Chin Tan

Yin Ping Wong

Affiliations

Soon will be listed here.

Abstract

chorioamnionitis is rarely encountered, even though vulvovaginal candidiasis incidence is about 15%. Interestingly, it has characteristic gross and histological findings on the umbilical cord that are not to be missed. We report two cases of chorioamnionitis with presence of multiple yellowish and red spots of the surface of the umbilical cord. Microscopically, these consist of microabscesses with evidence of fungal yeasts and pseudohyphae. The yeasts and pseudohyphae were highlighted by periodic acid- Schiff and Grocott methenamine silver histochemical stains. Both cases were associated with a history of gestational diabetes mellitus. Peripheral funisitis is a characteristic feature of chorioamnionitis. It is associated with high risk of adverse perinatal and neonatal outcomes, such as preterm delivery, stillbirth and neonatal death. We recommend careful examination of the umbilical cord of mothers with gestational diabetes mellitus.

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