A Clinician's Guide to Topical Retinoids

Overview

Journal J Cutan Med Surg

Publisher Sage Publications

Specialties Dermatology
General Surgery

Date 2021 Jul 22

PMID 34292058

Citations 16

Authors

Melika Motamedi

Ahmad Chehade

Ravina Sanghera

Parbeer Grewal

Affiliations

Soon will be listed here.

Abstract

Retinoids are defined as molecules that bind to and activate retinoic acid receptors to influence the proliferation and differentiation of cells. Topical retinoids have evolved over the past several decades, being used in multiple dermatological conditions. This review aims to differentiate between synthetic and natural retinoids, discuss the pharmacology behind topical retinoids, highlight clinical applications, and categorize all the commercially available agents, including combination products. Understanding retinoid affinities for unique receptor subtypes can impact clinical decisions, resulting in optimizing treatment and enhancing patient adherence.

Citing Articles

A prospective, double-blinded, randomized head-to-head clinical trial of topical adapinoid (oleyl adapalenate) versus retinol.

Nguyen N, Afzal N, Min M, Ahmad N, Afzal L, Burney W Skin Health Dis. 2024; 4(6):e469.

PMID: 39624736 PMC: 11608876. DOI: 10.1002/ski2.469.

A Comprehensive Review of the Strategies to Reduce Retinoid-Induced Skin Irritation in Topical Formulation.

Narsa A, Suhandi C, Afidika J, Ghaliya S, Elamin K, Wathoni N Dermatol Res Pract. 2024; 2024:5551774.

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Role of vitamin D supplement adjunct to topical benzoyl peroxide in acne: a randomized double-blinded controlled study.

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