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Factors Associated with Corneal High-order Aberrations Before and After Femtosecond Laser-assisted Keratomileusis

Overview
Journal Ann Transl Med
Date 2021 Jul 19
PMID 34277789
Citations 3
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Abstract

Background: Corneal high-order aberrations (HOAs) are related to visual quality. However, the factors associated with corneal HOAs before and after femtosecond laser-assisted in situ keratomileusis (FS-LASIK) have not yet been elucidated. The aim of this study is to observe the factors related to corneal HOAs before and after FS-LASIK.

Methods: Prospective observational study was designed to measure corneal HOAs in 149 eyes of 75 patients before and 6 months after FS-LASIK. The relationship between spherical diopter and corneal parameters, including K1 and K2 (horizontal and vertical refractive power of the cornea, respectively), the aspheric characteristics of the cornea (Q), mean radius of the curvature of the cornea (Rm), and central corneal thickness (CCT), with corneal HOAs were analyzed.

Results: The spherical diopter was correlated with trefoil at 30° before surgery and with vertical coma, four-order astigmatism at 0°, trefoil at 30°, spherical aberration, and six-order spherical aberration after surgery (P<0.05). CCT was correlated with vertical coma, four-order astigmatism at 0°, trefoil at 30°, and six-order spherical aberration after surgery (P<0.05). K1 was correlated with spherical aberration and six-order astigmatism at 0° before surgery (P<0.05). K2 was correlated with spherical aberration, six-order astigmatism at 45°, astigmatism at 0°, six-order astigmatism at 0° before surgery, and trefoil at 30° after surgery (P<0.05). Q was correlated with spherical aberration, six-order spherical aberration, and six-order astigmatism at 45° (P<0.05). Rm was correlated with six-order astigmatism at 0°, spherical aberration, six-order astigmatism at 45° before surgery, and astigmatism at 0° after surgery (P<0.05).

Conclusions: Corneal parameters and spherical diopter are related to the HOAs of the cornea before and after FS-LASIK.

Citing Articles

Effect of sodium fluorescein strip application on cornea parameters commonly used in laser-assisted in-situ keratomileusis.

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Comparison of myopic astigmatic correction after cross-assisted SMILE, FS-LASIK, and transPRK.

Yang Y, Li F, Wu S, Dai Q, Bao F, Cheng D J Cataract Refract Surg. 2023; 49(12):1242-1248.

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Analysis of Asphericity and Corneal Longitudinal Spherical Aberration of 915 Chinese Myopic Adult Eyes.

Zhang J, Zheng L, Zhang Y, Wang K Clin Ophthalmol. 2023; 17:591-600.

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