Comparative Analyses of the Subgingival Microbiome in Chronic Periodontitis Patients with and Without Gingival Erosive Oral Lichen Planus Based on 16S RRNA Gene Sequencing

Overview

Journal Biomed Res Int

Publisher Wiley

Specialties Biomedical Engineering
Biotechnology
General Medicine

Date 2021 Jul 14

PMID 34258290

Citations 3

Authors

Haohao Liu

Huiwen Chen

Yue Liao

Huxiao Li

Linjun Shi

Yiwen Deng

Xuemin Shen

Zhongchen Song

Affiliations

Soon will be listed here.

Abstract

The aim of the study was to compare the microbiota composition and bacterial diversity of subgingival plaque in chronic periodontitis patients with and without gingival erosive oral lichen planus. The subgingival plaque samples of 20 chronic periodontitis patients with gingival erosive oral lichen planus (CP-OLP group) and 19 chronic periodontitis patients without gingival erosive oral lichen planus (CP group) were analyzed by 16S rRNA gene high-throughput sequencing. Compared with the CP group, the richness and diversity of subgingival plaque microflora in the CP-OLP group decreased significantly. There were some differences between the two groups in the composition of microflora on the levels of phylum and genus. Distributions of and in the CP-OLP group were significantly lower than those in the CP group. The dominant genera in CP-OLP group were and . These results indicated that gingival erosive oral lichen planus may influence the structure and proportion of subgingival plaque microflora.

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