Larger Chondral Lesions Treated with Collagen Membrane - Matrix-Induced Autologous Chondrogenesis - Show Larger Increase in Clinical Scores

Overview

Journal Rev Bras Ortop (Sao Paulo)

Publisher Thieme

Specialty Orthopedics

Date 2021 Jul 9

PMID 34239198

Citations 2

Authors

Mateus Kenji Christo Miyahira

Joao Victor Novaretti

Diego Costa Astur

Camila Cohen Kaleka

Joicemar Tarouco Amaro

Moises Cohen

Affiliations

Soon will be listed here.

Abstract

To evaluate clinically and radiologically the results of the treatment of chondral lesions using collagen membrane - autologous matrix-induced chondrogenesis (AMIC). This is a series of observational cases, in which 15 patients undergoing AMIC were analyzed. The clinical evaluation was made by comparing the Lysholm and International Knee Document Commitee (IKDC) scores in the pre- and postoperative period of 12 months, and radiological evaluation using the Magnetic Resonance Observation of Cartilage Repair Tissue (MOCART) score in the same postoperative period. The mean age of the patients was 39.2 years old, and the mean size of the chondral lesions was 1.55cm . There was a significant improvement in clinical scores, with a mean increase of 24.6 points on Lysholm and of 24.3 on IKDC after 12 months. In the radiological evaluation, MOCART had a mean of 65 points. It was observed that the larger the size of the lesion, the greater the improvement in scores. Evaluating subjective clinical scores, the treatment of chondral lesions with the collagen membrane showed good results, as well as the evaluation of MOCART, with greater benefit in larger lesions.

Citing Articles

The efficacy of autologous matrix-induced chondrogenesis (AMIC) for osteochondral lesions of the talus in the mid-long term: a systematic review and meta-analysis.

Jiang N, Li H, Wang J, Shen L, Zeng X J Orthop Surg Res. 2024; 19(1):373.

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Autologous matrix-induced chondrogenesis is effective for focal chondral defects of the knee.

Migliorini F, Maffulli N, Baroncini A, Bell A, Hildebrand F, Schenker H Sci Rep. 2022; 12(1):9328.

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