Enzymatic Photoelectrochemical Bioassay Based on Hierarchical CdS/NiO Heterojunction for Glucose Determination

Overview

Journal Mikrochim Acta

Specialties Biotechnology
Chemistry

Date 2021 Jul 7

PMID 34231032

Authors

Hui-Yu Zou

Fen-Ying Kong

Xin-Yang Lu

Meng-Jiao Lu

Yuan-Cheng Zhu

Rui Ban

Wei-Wei Zhao

Wei Wang

Affiliations

Soon will be listed here.

Abstract

The design and development of a 3D hierarchical CdS/NiO heterojunction and its application in a self-powered cathodic photoelectrochemical (PEC) bioanalysis is introduced. Specifically, NiO nanoflakes (NFs) were in situ formed on carbon fibers via a facile liquid-phase deposition method followed by an annealing step and subsequent integration with CdS quantum dots (QDs). The glucose oxidase (GOx) was then coated on the photocathode to allow the determination of glucose. Under 5 W 410 nm LED light and at a working voltage of 0.0 V (vs. Ag/AgCl), this method can assay glucose concentrations down to 1.77×10 M. The linear range was 5×10 M to 1×10 M, and the relative standard deviation (RSD) was below 5%. The photocathodic biosensor achieved target detection with high sensitivity and selectivity. This work is expected to stimulate more passion in the development of innovative hierarchical heterostructures for advanced self-powered photocathodic bioanalysis. Design of 3D hierarchical CdS/NiO heterojunction and its application in a self-powered cathodic photoelectrochemical (PEC) bioanalysis.

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