Model Learning Analysis of 3D Optoacoustic Mesoscopy Images for the Classification of Atopic Dermatitis
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Atopic dermatitis (AD) is a skin inflammatory disease affecting 10% of the population worldwide. Raster-scanning optoacoustic mesoscopy (RSOM) has recently shown promise in dermatological imaging. We conducted a comprehensive analysis using three machine-learning models, random forest (RF), support vector machine (SVM), and convolutional neural network (CNN) for classifying healthy versus AD conditions, and sub-classifying different AD severities using RSOM images and clinical information. CNN model successfully differentiates healthy from AD patients with 97% accuracy. With limited data, RF achieved 65% accuracy in sub-classifying AD patients into mild versus moderate-severe cases. Identification of disease severities is vital in managing AD treatment.
Abdel-Mageed H Inflammopharmacology. 2025; .
PMID: 39918744 DOI: 10.1007/s10787-025-01642-z.
Li Pomi F, Papa V, Borgia F, Vaccaro M, Pioggia G, Gangemi S Life (Basel). 2024; 14(4).
PMID: 38672786 PMC: 11051135. DOI: 10.3390/life14040516.
Li X, Moothanchery M, Kwa C, Tan W, Yew Y, Thng S Photoacoustics. 2022; 28:100399.
PMID: 36090012 PMC: 9450137. DOI: 10.1016/j.pacs.2022.100399.
Xia J, Bell M, Laufer J, Yao J Biomed Opt Express. 2021; 12(7):4115-4118.
PMID: 34457402 PMC: 8367276. DOI: 10.1364/BOE.430421.