A Novel Computational Drug Repurposing Approach for Systemic Lupus Erythematosus (SLE) Treatment Using Semantic Web Technologies

Overview

Journal Saudi J Biol Sci

Specialty Biology

Date 2021 Jul 5

PMID 34220244

Citations 6

Authors

Adeeb Noor

Abdullah Assiri

Affiliations

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References

Ashburn T, Thor K . Drug repositioning: identifying and developing new uses for existing drugs. Nat Rev Drug Discov. 2004; 3(8):673-83. DOI: 10.1038/nrd1468. View

Fanouriakis A, Kostopoulou M, Alunno A, Aringer M, Bajema I, Boletis J . 2019 update of the EULAR recommendations for the management of systemic lupus erythematosus. Ann Rheum Dis. 2019; 78(6):736-745. DOI: 10.1136/annrheumdis-2019-215089. View

Bodenreider O . The Unified Medical Language System (UMLS): integrating biomedical terminology. Nucleic Acids Res. 2003; 32(Database issue):D267-70. PMC: 308795. DOI: 10.1093/nar/gkh061. View

Ashburner M, Ball C, Blake J, Botstein D, Butler H, Cherry J . Gene ontology: tool for the unification of biology. The Gene Ontology Consortium. Nat Genet. 2000; 25(1):25-9. PMC: 3037419. DOI: 10.1038/75556. View

Nalbandian A, Crispin J, Tsokos G . Interleukin-17 and systemic lupus erythematosus: current concepts. Clin Exp Immunol. 2009; 157(2):209-15. PMC: 2730846. DOI: 10.1111/j.1365-2249.2009.03944.x. View

Iudici M, Fasano S, Gabriele Falcone L, Pantano I, La Montagna G, Migliaresi S . Low-dose aspirin as primary prophylaxis for cardiovascular events in systemic lupus erythematosus: a long-term retrospective cohort study. Rheumatology (Oxford). 2016; 55(9):1623-30. DOI: 10.1093/rheumatology/kew231. View

Graul A, Cruces E . The year's new drugs & biologics, 2010. Drugs Today (Barc). 2011; 47(1):27-51. DOI: 10.1358/dot.2011.47.1.1587820. View

Rizvi R, Hojjati M . Interferon-α induced lupus in a patient with chronic hepatitis C virus. J Clin Rheumatol. 2011; 17(3):152-3. DOI: 10.1097/RHU.0b013e31821557e7. View

Noor A, Assiri A, Ayvaz S, Clark C, Dumontier M . Drug-drug interaction discovery and demystification using Semantic Web technologies. J Am Med Inform Assoc. 2016; 24(3):556-564. PMC: 7651897. DOI: 10.1093/jamia/ocw128. View

10.

Collins F . Mining for therapeutic gold. Nat Rev Drug Discov. 2011; 10(6):397. PMC: 5101935. DOI: 10.1038/nrd3461. View

11.

Assiri A, Noor A . A computational approach to predict multi-pathway drug-drug interactions: A case study of irinotecan, a colon cancer medication. Saudi Pharm J. 2021; 28(12):1507-1513. PMC: 7783232. DOI: 10.1016/j.jsps.2020.09.017. View

12.

de Coronado S, Haber M, Sioutos N, Tuttle M, Wright L . NCI Thesaurus: using science-based terminology to integrate cancer research results. Stud Health Technol Inform. 2004; 107(Pt 1):33-7. View

13.

Parks C, Cooper G, Dooley M, Treadwell E, St Clair E, Gilkeson G . Systemic lupus erythematosus and genetic variation in the interleukin 1 gene cluster: a population based study in the southeastern United States. Ann Rheum Dis. 2003; 63(1):91-4. PMC: 1754721. DOI: 10.1136/ard.2003.007336. View

14.

Qu X, Gudivada R, Jegga A, Neumann E, Aronow B . Inferring novel disease indications for known drugs by semantically linking drug action and disease mechanism relationships. BMC Bioinformatics. 2009; 10 Suppl 5:S4. PMC: 2679404. DOI: 10.1186/1471-2105-10-S5-S4. View

15.

Yilmaz S, Cimen K . Pegylated interferon alpha-2B induced lupus in a patient with chronic hepatitis B virus infection: case report. Clin Rheumatol. 2009; 28(10):1241-3. DOI: 10.1007/s10067-009-1239-3. View

16.

Klein T, Chang J, Cho M, Easton K, Fergerson R, Hewett M . Integrating genotype and phenotype information: an overview of the PharmGKB project. Pharmacogenetics Research Network and Knowledge Base. Pharmacogenomics J. 2002; 1(3):167-70. DOI: 10.1038/sj.tpj.6500035. View

17.

Brown S, Elkin P, Rosenbloom S, Husser C, Bauer B, Lincoln M . VA National Drug File Reference Terminology: a cross-institutional content coverage study. Stud Health Technol Inform. 2004; 107(Pt 1):477-81. View

18.

Zhang C, Zhao M, Liu J, Huang Q, Li P, Ni J . Association of lymphotoxin alpha polymorphism with systemic lupus erythematosus and rheumatoid arthritis: a meta-analysis. Int J Rheum Dis. 2015; 18(4):398-407. DOI: 10.1111/1756-185X.12588. View

19.

Morgan S, Grootendorst P, Lexchin J, Cunningham C, Greyson D . The cost of drug development: a systematic review. Health Policy. 2011; 100(1):4-17. DOI: 10.1016/j.healthpol.2010.12.002. View

20.

Akdogan A, Kilic L, Akman U, Dogan I, Karadag O, Bilgen S . Aspirin resistance in systemic lupus erythematosus. A pilot study. Lupus. 2013; 22(8):835-8. DOI: 10.1177/0961203313493487. View