Studies on the Heterophile Antibodies of Infectious Mononucleosis. I. Separation of Four Antibody Populations, One of Which Contains Lymphocytotoxic Activity

Overview

Journal Clin Exp Immunol

Publisher Oxford University Press

Specialty Allergy & Immunology

Date 1977 Dec 1

PMID 342158

Citations 3

Authors

J Langhorne

T Feizi

Affiliations

Soon will be listed here.

Abstract

With the aid of insolubilized immunoadsorbents made with glycoproteins, extracted from cow red blood cells (RBC), and with guinea-pig kidney tissue, heterophile antibody populations of the Paul--Bunnell type and the Forssman type were eluted from infectious mononucleosis sera. Two Paul--Bunnell-type antibody populations were separated on the basis of their affinity for cow RBC antigens. The lymphocytotoxic antibodies in the infectious mononucleosis sera were eluted among the low-affinity Paul--Bunnell antibodies.

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