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Advances in Supercritical Carbon Dioxide Extraction of Bioactive Substances from Different Parts of L

Overview
Journal Molecules
Publisher MDPI
Specialty Biology
Date 2021 Jul 2
PMID 34209219
Citations 10
Authors
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Abstract

L. has always been a popular area of research due to its various active ingredients and pharmacological effects. is rich in ginkgo flavonoids, ginkgolides, and ginkgolic acid, with anti-inflammation, antioxidation, neuroprotection, anti-platelet agglutination, hypolipidemic effect, anti-cancer, and anti-radiation properties. There are many methods to extract and separate the active components of ginkgo. Among them, supercritical carbon dioxide fluid extraction (SFE-CO) is known for its green, clean, and environment-friendly properties. In this paper, the pharmacological activities, the active components, and structures of different parts of ginkgo, the extraction methods of its effective ingredients, and the application of the SFE-CO method for the extraction and separation of active ingredients in from leaves, seeds, pollen, and roots were reviewed, in order to make best use of ginkgo resources, and provide support and references for the development of SFE-CO of active components from .

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References
1.
Li Y, Wu Y, Yao X, Hao F, Yu C, Bao Y . Ginkgolide A Ameliorates LPS-Induced Inflammatory Responses In Vitro and In Vivo. Int J Mol Sci. 2017; 18(4). PMC: 5412378. DOI: 10.3390/ijms18040794. View

2.
Yao H, Du X, Yang L, Wang W, Yang F, Zhao C . Microwave-assisted method for simultaneous extraction and hydrolysis for determination of flavonol glycosides in Ginkgo foliage using Brönsted acidic ionic-liquid [HO(3)S(CH(2))(4)mim]HSO(4) aqueous solutions. Int J Mol Sci. 2012; 13(7):8775-8788. PMC: 3430265. DOI: 10.3390/ijms13078775. View

3.
Lei H, Shi Q, Ge F, Pan J . [Supercritical CO2 extraction of fatty oils from bee pollen and its GC-MS analysis]. Zhong Yao Cai. 2004; 27(3):177-80. View

4.
Longo R, Blackman J, Torley P, Rogiers S, Schmidtke L . Changes in volatile composition and sensory attributes of wines during alcohol content reduction. J Sci Food Agric. 2016; 97(1):8-16. DOI: 10.1002/jsfa.7757. View

5.
Wrona O, Rafinska K, Mozenski C, Buszewski B . Supercritical Fluid Extraction of Bioactive Compounds from Plant Materials. J AOAC Int. 2017; 100(6):1624-1635. DOI: 10.5740/jaoacint.17-0232. View