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An Overview on Topical Administration of Carotenoids and Coenzyme Q10 Loaded in Lipid Nanoparticles

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Date 2021 Jul 2
PMID 34206935
Citations 11
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Abstract

Carotenoids and coenzyme Q10 are naturally occurring antioxidant compounds that are also found in human skin. These bioactive compounds have been the focus of considerable research due to their antioxidant, anti-inflammatory, and photoprotective properties. In this review, the current state of the art in the encapsulation of carotenoids and coenzyme Q10 in lipid nanoparticles to improve their bioavailability, chemical stability, and skin absorption is discussed. Additionally, the main findings are highlighted on the cytotoxic and photoprotective effects of these systems in the skin.

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References
1.
Balic A, Mokos M . Do We Utilize Our Knowledge of the Skin Protective Effects of Carotenoids Enough?. Antioxidants (Basel). 2019; 8(8). PMC: 6719967. DOI: 10.3390/antiox8080259. View

2.
Muller R, Petersen R, Hommoss A, Pardeike J . Nanostructured lipid carriers (NLC) in cosmetic dermal products. Adv Drug Deliv Rev. 2007; 59(6):522-30. DOI: 10.1016/j.addr.2007.04.012. View

3.
Trombino S, Cassano R, Muzzalupo R, Pingitore A, Cione E, Picci N . Stearyl ferulate-based solid lipid nanoparticles for the encapsulation and stabilization of beta-carotene and alpha-tocopherol. Colloids Surf B Biointerfaces. 2009; 72(2):181-7. DOI: 10.1016/j.colsurfb.2009.03.032. View

4.
Nik A, Langmaid S, Wright A . Nonionic surfactant and interfacial structure impact crystallinity and stability of β-carotene loaded lipid nanodispersions. J Agric Food Chem. 2012; 60(16):4126-35. DOI: 10.1021/jf204810m. View

5.
Bhagavan H, Chopra R . Coenzyme Q10: absorption, tissue uptake, metabolism and pharmacokinetics. Free Radic Res. 2006; 40(5):445-53. DOI: 10.1080/10715760600617843. View