Albumin Acts As a Lubricant on the Surface of Hydrogel and Silicone Hydrogel Contact Lenses

Overview

Journal Polymers (Basel)

Publisher MDPI

Date 2021 Jul 2

PMID 34201543

Citations 2

Authors

Chen-Ying Su

Lung-Kun Yeh

Tzu-Wei Fan

Chi-Chun Lai

Hsu-Wei Fang

Affiliations

Soon will be listed here.

Abstract

Feeling comfortable is the greatest concern for contact lens wearers, and it has been suggested that in vivo comfort could be corresponded to the in vitro friction coefficient of contact lenses. How tear albumin could affect the friction coefficient of silicone hydrogel and hydrogel contact lenses was analyzed by sliding a lens against a quartz glass in normal and extremely high concentration of albumin solution. Albumin deposition testing and surface roughness analysis were also conducted. The results showed that the friction coefficient of tested contact lenses did not correspond to both the albumin deposition amount and surface roughness, but we proposed a model of how albumin might act as a lubricant on the surface of some hydrogel and silicone hydrogel contact lenses. In conclusion, albumin provided lubrication for silicone hydrogel contact lenses regardless of albumin concentrations, while albumin only acted as a lubricant for hydrogel contact under normal concentration.

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