Sample Size Determination in Studies with Matched Pairs

Overview

Journal J Clin Epidemiol

Publisher Elsevier

Specialty Public Health

Date 1988 Jan 1

PMID 3418361

Citations 4

Authors

J L Fleiss

B Levin

Affiliations

Soon will be listed here.

Abstract

Two modifications are made in Schlesselman's procedure for determining the total number of pairs to be studied in a case-control study with matching. One is to take account of the use of the continuity correction in the McNemar test statistic, and the other is to incorporate a measure of the degree of association induced by the matching variables between a case's exposure status and that of his or her matched control. The result of both modifications is to increase the required number of pairs above the number produced by Schlesselman's procedure.

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