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Quantitative Genetics: Pan-genomes, SVs, and K-mers for GWAS

Overview
Journal Trends Genet
Specialty Genetics
Date 2021 Jun 29
PMID 34183185
Citations 8
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Abstract

For identification of marker-trait associations (MTAs) for complex traits in animals and plants, thousands of genome-wide association studies (GWAS) were conducted during the past two decades. This involved regular improvement in methodology. Initially, a reference genome and SNPs were used; more recently pan-genomes and the markers structural variations (SVs)/k-mers are also being used.

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