Opto-refrigerative Tweezers

Overview

Journal Sci Adv

Specialties Biology
Science

Date 2021 Jun 26

PMID 34172454

Citations 13

Authors

Jingang Li

Zhihan Chen

Yaoran Liu

Pavana Siddhartha Kollipara

Yichao Feng

Zhenglong Zhang

Yuebing Zheng

Affiliations

Soon will be listed here.

Abstract

Optical tweezers offer revolutionary opportunities for both fundamental and applied research in materials science, biology, and medical engineering. However, the requirement of a strongly focused and high-intensity laser beam results in potential photon-induced and thermal damages to target objects, including nanoparticles, cells, and biomolecules. Here, we report a new type of light-based tweezers, termed opto-refrigerative tweezers, which exploit solid-state optical refrigeration and thermophoresis to trap particles and molecules at the laser-generated cold region. While laser refrigeration can avoid photothermal heating, the use of a weakly focused laser beam can further reduce the photodamages to the target object. This novel and noninvasive optical tweezing technique will bring new possibilities in the optical control of nanomaterials and biomolecules for essential applications in nanotechnology, photonics, and life science.

Citing Articles

Photopyroelectric tweezers for versatile manipulation.

Wang F, Liu C, Dai Z, Xu W, Ma X, Gao Y Innovation (Camb). 2025; 6(1):100742.

PMID: 39872479 PMC: 11763915. DOI: 10.1016/j.xinn.2024.100742.

Recent Advancements in Nanophotonics for Optofluidics.

Yang S, Hong C, Zhu G, Anyika T, Hong I, Ndukaife J Adv Phys X. 2024; 9(1).

PMID: 39554474 PMC: 11563312. DOI: 10.1080/23746149.2024.2416178.

Thermo-optical tweezers based on photothermal waveguides.

Li F, Wei J, Qin X, Chen X, Chen D, Zhang W Microsyst Nanoeng. 2024; 10(1):123.

PMID: 39223148 PMC: 11368956. DOI: 10.1038/s41378-024-00757-7.

Optothermal Needle-Free Injection of Vaterite Nanocapsules.

Kislov D, Ofer D, Machnev A, Barhom H, Bobrovs V, Shalin A Adv Sci (Weinh). 2023; 11(5):e2305202.

PMID: 38044325 PMC: 10837343. DOI: 10.1002/advs.202305202.

Hypothermal opto-thermophoretic tweezers.

Kollipara P, Li X, Li J, Chen Z, Ding H, Kim Y Nat Commun. 2023; 14(1):5133.

PMID: 37612299 PMC: 10447564. DOI: 10.1038/s41467-023-40865-y.

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