Evaluation of Neutrophil/lymphocyte Ratio, Platelet/lymphocyte Ratio, Mean Platelet Volume, and Neutrophil/monocyte Ratio in Patients with Benign Breast Lesions

Objectives: In this study, we aimed to demonstrate the relationship between he neutrophil/lymphocyte ratio (NLR), platelet/lymphocyte ratio (PLR), neutrophil/monocyte rate (NMR) and mean platelet volume (MPV) in patients with BIRADS grades of benign breast lesions.

Background: In many recent studies, NLR, PLR, NMR and MPV change significantly in connection with chronic inflammation and are suggested for use as prognostic markers in some diseases. However, the relationship between the cancer probability of benign breast diseases and mentioned hematological parameters has not been investigated in any previous study. We used the BIRADS classification to evaluate the malignancy probability of the cases.

Methods: The hospital database of records of patients who were over 15 years of age and examined with bilateral ultrasonography between October 2019 and February 2020 were retrospectively scanned.

Results: In total, 168 patients were included in the study. The average NLR and NMR values were higher in the BIRADS 2 group. There was no significant difference between the average PLR and MPV values of BIRADS groups.

Conclusions: Although some results seem to be statistically significant, there was no significant relationship between the hematological parameters we examined and the BIRADS grades of benign breast lesions (Tab. 2, Ref. 18).