Is White the Right Light for the Clinical Electrooculogram?

Overview

Journal Doc Ophthalmol

Specialty Ophthalmology

Date 2021 Jun 23

PMID 34160736

Citations 1

Authors

Paul A Constable

Garima Kapoor

Affiliations

Soon will be listed here.

Abstract

Purpose: To investigate if a lower luminance monochromatic LED stimulus could be used as an alternative to a high luminance white light for the clinical electrooculogram.

Methods: Clinical electrooculograms were recorded in color normal participants (N = 23) aged 22.6 ± 1.2 years, 7 male and 16 female using the standard 100 cd.m white illuminant and four monochromatic LEDs with peak wavelengths of 448, 534, 596 and 634 nm at 30 cd.m. Pupils were dilated and there was a 30 cd.mpre-adaptation to white light for 2 min followed by 15 min dark adaptation and 20 min recording in the light stimulus using a Ganzfeld stimulator.

Results: The normalized LP:DTratio for the short wavelength LED (448 nm) was equivalent in amplitude and timing to the ISCEV standard EOG (p = .99). The LP:DTratio for the white (100 cd.m) and 448 nm (30 cd.m) were (median ± SEM): 2.49 ± .11 and 2.47 ± .11. The time to light-rise peak was also equivalent being 9.0 ± .2 and 8.0 ± .4 min (p = .54).

Conclusions: Consideration may be given to using a short wavelength monochromatic stimulus that is more comfortable for the subject than the current 100 cd.m illuminant.

Citing Articles

Retinal electrophysiology in central nervous system disorders. A review of human and mouse studies.

Constable P, Lim J, Thompson D Front Neurosci. 2023; 17:1215097.

PMID: 37600004 PMC: 10433210. DOI: 10.3389/fnins.2023.1215097.

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