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Long-Term Treatment of Postmenopausal Osteoporosis

Overview
Specialty Endocrinology
Date 2021 Jun 21
PMID 34154042
Citations 49
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Abstract

Osteoporosis is an incurable chronic condition, like heart disease, diabetes, or hypertension. A large gap currently exists in the primary prevention of fractures, and studies show that an estimated 80% to 90% of adults do not receive appropriate osteoporosis management even in the secondary prevention setting. Case finding strategies have been developed and effective pharmacological interventions are available. This publication addresses how best to use the pharmacological options available for postmenopausal osteoporosis to provide lifelong fracture protection in patients at high and very high risk of fracture. The benefit of osteoporosis therapies far outweighs the rare risks.

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References
1.
Kim H, Jang E, Park B, Kim T, Shin S, Ha Y . Development of a Korean Fracture Risk Score (KFRS) for Predicting Osteoporotic Fracture Risk: Analysis of Data from the Korean National Health Insurance Service. PLoS One. 2016; 11(7):e0158918. PMC: 4939957. DOI: 10.1371/journal.pone.0158918. View

2.
Miller P, Pannacciulli N, Brown J, Czerwinski E, Nedergaard B, Bolognese M . Denosumab or Zoledronic Acid in Postmenopausal Women With Osteoporosis Previously Treated With Oral Bisphosphonates. J Clin Endocrinol Metab. 2016; 101(8):3163-70. PMC: 4971333. DOI: 10.1210/jc.2016-1801. View

3.
McCloskey E, Kanis J, Johansson H, Harvey N, Oden A, Cooper A . FRAX-based assessment and intervention thresholds--an exploration of thresholds in women aged 50 years and older in the UK. Osteoporos Int. 2015; 26(8):2091-9. DOI: 10.1007/s00198-015-3176-0. View

4.
Ng A, Png M, Mohan P, Koh J, Howe T . Atypical femoral fractures: transverse morphology at lateral cortex is a critical feature. J Bone Miner Res. 2013; 29(3):639-43. DOI: 10.1002/jbmr.2078. View

5.
Metcalfe D, Zogg C, Judge A, Perry D, Gabbe B, Willett K . Pay for performance and hip fracture outcomes: an interrupted time series and difference-in-differences analysis in England and Scotland. Bone Joint J. 2019; 101-B(8):1015-1023. PMC: 6683232. DOI: 10.1302/0301-620X.101B8.BJJ-2019-0173.R1. View