Extracorporeal Membrane Oxygenation (ECMO) for Acute Exacerbations of Chronic Obstructive Pulmonary Disease: Care Modalities, Experience, and Precautions

Overview

Journal Am J Transl Res

Specialty General Medicine

Date 2021 Jun 21

PMID 34150076

Citations 1

Authors

Yaoji Wang

Pingping Cao

Affiliations

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Abstract

Purpose: The aim of this study was to summarize the care modalities, experiences, and corresponding precautions of ECMO for acute exacerbations of chronic obstructive pulmonary disease (COPD).

Methods: Seventy-three patients with acute exacerbations of COPD were enrolled, of whom 38 were treated with ECMO (experimental group) and 35 received conventional low-flow oxygen therapy, management of metabolic acidosis, infection control, bronchodilators for quick relief from severe spasms, and glucocorticoid-mediated suppression of inflammation (control group). The improvement in the patient's pulmonary ventilation and the incidence of complications were recorded.

Results: PaCO is lower in patients using ECMO, FEV1, FEV1/FVC, and FEV1% are significantly higher in the experimental group than in the control group, and the respiratory rate, heart rate, and CO saturation are significantly lower in patients in the experimental group (i.e., the experimental group) after oxygenation than in the control group, pH and O saturation are significantly higher in experimental group than in the control group, and the incidence of complications in experimental group is significantly higher than in the control group.

Conclusion: ECMO significantly improves gas exchange in patients, but also increases the incidence of complications with the extension of usage, so the duration of ECMO support should be monitored and the complications should be prevented.

Citing Articles

Extracorporeal membrane oxygenation for adults with respiratory failure secondary to cardiorespiratory disease: evolving indications and clinical practice.

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COPD Exacerbation: Why It Is Important to Avoid ICU Admission.

Prediletto I, Giancotti G, Nava S J Clin Med. 2023; 12(10).

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