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Considerations for the Design of Pre-exposure Prophylaxis (PrEP) Interventions for Women: Lessons Learned from the Implementation of a Novel PrEP Intervention

Overview
Journal AIDS Behav
Date 2021 Jun 17
PMID 34138377
Citations 20
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Abstract

Pre-exposure prophylaxis (PrEP) uptake among women in the United States has been low. To increase uptake, we developed a peer outreach and navigation PrEP intervention. Semi-structured qualitative interviews with 32 cisgender women and 3 transgender women were conducted to assess the intervention. We used a thematic approach to identify barriers to, and facilitators of the intervention. Facilitators included interest in PrEP, offer of health and social services, the intervention's women-focused approach, and peer outreach and navigation. Barriers were perceived HIV risk, concerns about medication side effects or interactions, housing insecurity and travel, co-occurring health-related conditions, and caregiving responsibilities. We recommend that future interventions consider packaging PrEP in local community settings, such as syringe exchange programs; include services such as food and housing assistance; use peers to recruit and educate women; integrate a culturally appropriate women's focus; and consider providing same-day PrEP.

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References
1.
Rowan S, Patel R, Schneider J, Smith D . Same-day prescribing of daily oral pre-exposure prophylaxis for HIV prevention. Lancet HIV. 2020; 8(2):e114-e120. DOI: 10.1016/S2352-3018(20)30256-3. View

2.
Walters S, Seal D, Stopka T, Murphy M, Jenkins W . COVID-19 and People Who Use Drugs - A Commentary. Health Behav Policy Rev. 2020; 7(5):489-497. PMC: 7595339. DOI: 10.14485/hbpr.7.5.11. View

3.
Lee R, Cui R, Muessig K, Thirumurthy H, Tucker J . Incentivizing HIV/STI testing: a systematic review of the literature. AIDS Behav. 2013; 18(5):905-12. PMC: 3966986. DOI: 10.1007/s10461-013-0588-8. View

4.
Evans J, Hahn J, Page-Shafer K, Lum P, Stein E, Davidson P . Gender differences in sexual and injection risk behavior among active young injection drug users in San Francisco (the UFO Study). J Urban Health. 2003; 80(1):137-46. PMC: 3456106. DOI: 10.1093/jurban/jtg137. View

5.
Herbst J, Jacobs E, Finlayson T, McKleroy V, Neumann M, Crepaz N . Estimating HIV prevalence and risk behaviors of transgender persons in the United States: a systematic review. AIDS Behav. 2007; 12(1):1-17. DOI: 10.1007/s10461-007-9299-3. View