Cerebellar Venous Thrombosis Mimicking a Cerebellar Tumor Due to Polycythemia Vera: a Case Report

Overview

Journal BMC Neurol

Publisher Biomed Central

Specialty Neurology

Date 2021 Jun 17

PMID 34134639

Citations 1

Authors

Hongfeng Wen

Di Jin

Yu Chen

Bin Cui

Tianyi Xiao

Affiliations

Soon will be listed here.

Abstract

Background: Cerebral venous thrombosis (CVT) occurs rarely in the general population and is frequently associated with confused clinical findings and delayed diagnosis. Isolated cerebellar cortical vein thrombosis is a very rare phenomenon.

Case Presentation: This report describes a case with CVT, which is manifested as space-occupying lesions of the cerebellar hemisphere and mimics a cerebellar tumor at the beginning. The diagnosis of CVT was finalized given the laboratory and brain biopsy findings. The etiology may be related to polycythemia vera with Janus Kinase 2 V617F mutation.

Conclusion: Isolated cerebellar vein thrombosis should be considered when swelling and enhancing cerebellar lesions are detected. Polycythemia vera, especially with a positive JAK2 V617F mutation, may be a rare risk factor for CVT.

Citing Articles

Diagnosis and Management of Cerebral Venous Thrombosis Due to Polycythemia Vera and Genetic Thrombophilia: Case Report and Literature Review.

Jianu D, Jianu S, Iacob N, Dan T, Munteanu G, Gogu A Life (Basel). 2023; 13(5).

PMID: 37240720 PMC: 10223030. DOI: 10.3390/life13051074.

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