Large Variation in Anti-SARS-CoV-2 Antibody Prevalence Among Essential Workers in Geneva, Switzerland

Overview

Journal Nat Commun

Specialty Biology

Date 2021 Jun 9

PMID 34103517

Citations 23

Authors

Silvia Stringhini

Maria-Eugenia Zaballa

Nick Pullen

Carlos de Mestral

Javier Perez-Saez

Roxane Dumont

Attilio Picazio

Francesco Pennacchio

Yaron Dibner

Sabine Yerly

Helene Baysson

Nicolas Vuilleumier

Jean-Francois Balavoine

Delphine Bachmann

Didier Trono

Didier Pittet

Francois Chappuis

Omar Kherad

Laurent Kaiser

Andrew S Azman

Idris Guessous

Affiliations

Soon will be listed here.

Abstract

Limited data exist on SARS-CoV-2 infection rates across sectors and occupations, hindering our ability to make rational policy, including vaccination prioritization, to protect workers and limit SARS-CoV-2 spread. Here, we present results from our SEROCoV-WORK + study, a serosurvey of workers recruited after the first wave of the COVID-19 pandemic in Geneva, Switzerland. We tested workers (May 18-September 18, 2020) from 16 sectors and 32 occupations for anti-SARS-CoV-2 IgG antibodies. Of 10,513 participants, 1026 (9.8%) tested positive. The seropositivity rate ranged from 4.2% in the media sector to 14.3% in the nursing home sector. We found considerable within-sector variability: nursing home (0%-31.4%), homecare (3.9%-12.6%), healthcare (0%-23.5%), public administration (2.6%-24.6%), and public security (0%-16.7%). Seropositivity rates also varied across occupations, from 15.0% among kitchen staff and 14.4% among nurses, to 5.4% among domestic care workers and 2.8% among journalists. Our findings show that seropositivity rates varied widely across sectors, between facilities within sectors, and across occupations, reflecting a higher exposure in certain sectors and occupations.

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