Frequency of Aspirin Resistance in Ischemic Stroke Patients and Healthy Controls from Colombia

Overview

Journal Stroke Res Treat

Publisher Wiley

Date 2021 Jun 7

PMID 34094500

Citations 1

Authors

Alejandro Roman-Gonzalez

Carlos Andres Naranjo

Walter D Cardona-Maya

Dionis Vallejo

Francisco Garcia

Cesar Franco

Leonor Alvarez

Luis Ignacio Tobon

Marta Ibeth Lopez

Carolina Rua

Gabriel Bedoya

Angela Cadavid

Jose Domingo Torres

Affiliations

Soon will be listed here.

Abstract

Objective: To evaluate the aspirin resistance prevalence in patients with previous ischemic cerebrovascular disease undergoing aspirin therapy for secondary prevention.

Materials And Methods: Three hundred fifty patients presenting ischemic strokes and 100 healthy controls under aspirin treatment were evaluated using the optic platelet aggregation test.

Results: Aspirin resistance was found in 7.4% of the patients with ischemic stroke and 4% of controls. Aspirin resistance was associated with stroke recurrence in univariate analysis ( = 0.004). Aspirin resistance was not associated with smoking, diabetes, or hypercholesterolemia.

Conclusion: Aspirin resistance is present in Colombian patients with ischemic stroke as well as in healthy controls.

Citing Articles

Long-Term Effect of Left Atrial Appendage Occlusion in Treating Patients with Previous Ischemic Stroke on the Disease Recurrence.

Yu J, Liu Y, Sun P, Guo X, Jiang H, Fang W Comput Math Methods Med. 2021; 2021:6991002.

PMID: 34691240 PMC: 8528575. DOI: 10.1155/2021/6991002.

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