Computed Tomography-guided Marking Using a Dye-staining Method for Preoperative Localization of Tiny Pulmonary Lesions in Children

Overview

Journal Pediatr Surg Int

Specialties General Surgery
Pediatrics

Date 2021 Jun 6

PMID 34091750

Citations 7

Authors

Taku Yamamichi

Masanori Nishikawa

Keita Takayama

Koki Takase

Kiyokazu Kim

Satoshi Umeda

Ai Tayama

Ryo Tsukada

Motonari Nomura

Hiroomi Okuyama

Noriaki Usui

Affiliations

Soon will be listed here.

Abstract

Purpose: It is important to confirm the existence of pulmonary metastases in pediatric patients with malignancies. Therefore, we aimed to investigate if computed tomography CT-guided marking is a feasible and safe method for the identification and resection of tiny pulmonary lesions in pediatric cancer patients.

Methods: We retrospectively reviewed the medical records of pediatric cancer patients who underwent CT-guided marking procedures in our institutions between Jan 2011 and Apr 2020. After 2015, these procedures were combined with an indocyanine green (ICG) navigation-guided surgery for hepatoblastoma cases.

Results: We targeted a total of 22 nodules in 12 patients. Of these, marking was successful in 18 (81.8%) nodules, 10 of which contained viable malignant cells. Complications caused by the marking procedures included mild pneumothorax and mild atelectasis in two patients, respectively. Of the eight resected nodules in patients with hepatoblastoma, four were ICG-positive and contained viable malignant cells. Two additional ICG-positive nodules, which were unidentified before surgery, were observed intraoperatively.

Conclusion: CT-guided marking is a feasible and safe method that can be used to identify and resect tiny pulmonary lesions in pediatric cancer patients. An ICG navigation-guided surgery is useful when combined with CT-guided marking, particularly in hepatoblastoma cases.

Citing Articles

Current trends and prospects of surgical techniques for hepatoblastoma.

Pu J, Li H, Li S, Wang Y, Li S, Tang S Cancer Med. 2024; 13(1):e6795.

PMID: 38180290 PMC: 10807562. DOI: 10.1002/cam4.6795.

Identification of Pediatric Tumors Intraoperatively Using Indocyanine Green (ICG).

Pio L, Wijnen M, Giuliani S, Sarnacki S, Davidoff A, Abdelhafeez A Ann Surg Oncol. 2023; 30(12):7789-7798.

PMID: 37543553 DOI: 10.1245/s10434-023-13953-y.

Thoracoscopic Resection of Lung Nodules following CT-Guided Labeling in Children and Adolescents with Solid Tumors.

Warmann S, Lieber J, Schaefer J, Ebinger M, Urla C, Kirschner H Children (Basel). 2023; 10(3).

PMID: 36980100 PMC: 10047192. DOI: 10.3390/children10030542.

Recent advances in surgical strategies and liver transplantation for hepatoblastoma.

Honda M, Uchida K, Irie T, Hirukawa K, Kadohisa M, Shimata K Cancer Med. 2022; 12(4):3909-3918.

PMID: 36394165 PMC: 9972171. DOI: 10.1002/cam4.5300.

Tumor-Background Ratio is an effective method to identify tumors and false-positive nodules in indocyanine-green navigation surgery for pediatric liver cancer.

Feng J, Qin H, Yang W, Cheng H, Xu J, Han J Front Pediatr. 2022; 10:875688.

PMID: 35967548 PMC: 9363659. DOI: 10.3389/fped.2022.875688.

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