Health-Related Quality of Life in Adult Spanish Women with Endometriomas or Deep Infiltrating Endometriosis: A Case-Control Study

Overview

Journal Int J Environ Res Public Health

Publisher MDPI

Specialties Environmental Health
Public Health

Date 2021 Jun 2

PMID 34073723

Citations 4

Authors

Evdochia Adoamnei

Ines Moran-Sanchez

Maria Luisa Sanchez-Ferrer

Jaime Mendiola

Maria Teresa Prieto-Sanchez

Miriam Monino-Garcia

Joaquin A Palomar-Rodriguez

Alberto Manuel Torres-Cantero

Affiliations

Soon will be listed here.

Abstract

Endometriosis is a disabling disease that may significantly compromise a woman's social relationships, sexuality, and mental health. Considering the impact of endometriomas and deep infiltrating endometriosis (DIE) on quality of life and the limited number of papers on this topic, the objective of this study was to assess health-related quality of life (HRQoL) in adult Spanish women with the condition. A case-control study was conducted on a group of 99 patients with ovarian endometriomas or DIE and 157 controls. Women underwent physical and gynecological examinations, and they completed health questionnaires including the Short Form-12v2 (SF-12v2), a survey for HRQoL. Eight scales and two component summary scores (Physical (PCS) and Mental (MCS), respectively) were calculated. Women with endometriomas or DIE had significantly worse PCS: 47.7 ± 9.7 vs. 56.1 ± 5.9, respectively ( < 0.001) compared to controls, as well as lower scores on seven out of the eight scales ( < 0.01). No significant differences were found for the MCS. Conclusions: HRQoL was significantly lower in patients with endometriomas or DIE compared to controls. If confirmed, these results may have important implications for prevention, clinical practice, and intervention.

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References

Buck Louis G, Hediger M, Peterson C, Croughan M, Sundaram R, Stanford J . Incidence of endometriosis by study population and diagnostic method: the ENDO study. Fertil Steril. 2011; 96(2):360-5. PMC: 3143230. DOI: 10.1016/j.fertnstert.2011.05.087. View

Guerriero S, Mais V, Ajossa S, Melis G . Predictive value of color Doppler for ovarian endometrioma. Fertil Steril. 1995; 63(5):1136-7. DOI: 10.1016/s0015-0282(16)57567-0. View

Koninckx P, Ussia A, Adamyan L, Wattiez A, Donnez J . Deep endometriosis: definition, diagnosis, and treatment. Fertil Steril. 2012; 98(3):564-71. DOI: 10.1016/j.fertnstert.2012.07.1061. View

Jones G, Jenkinson C, Kennedy S . The impact of endometriosis upon quality of life: a qualitative analysis. J Psychosom Obstet Gynaecol. 2005; 25(2):123-33. DOI: 10.1080/01674820400002279. View

Soliman A, Singh S, Rahal Y, Robert C, Defoy I, Nisbet P . Cross-Sectional Survey of the Impact of Endometriosis Symptoms on Health-Related Quality of Life in Canadian Women. J Obstet Gynaecol Can. 2020; 42(11):1330-1338. DOI: 10.1016/j.jogc.2020.04.013. View

Contopoulos-Ioannidis D, Karvouni A, Kouri I, Ioannidis J . Reporting and interpretation of SF-36 outcomes in randomised trials: systematic review. BMJ. 2009; 338:a3006. PMC: 2628302. DOI: 10.1136/bmj.a3006. View

Rees M, Kiemle G, Slade P . Psychological variables and quality of life in women with endometriosis. J Psychosom Obstet Gynaecol. 2020; 43(1):58-65. DOI: 10.1080/0167482X.2020.1784874. View

Fourquet J, Baez L, Figueroa M, Iriarte R, Flores I . Quantification of the impact of endometriosis symptoms on health-related quality of life and work productivity. Fertil Steril. 2011; 96(1):107-12. PMC: 3129383. DOI: 10.1016/j.fertnstert.2011.04.095. View

Pessoa de Farias Rodrigues M, Vilarino F, de Souza Barbeiro Munhoz A, da Silva Paiva L, Sousa L, Zaia V . Clinical aspects and the quality of life among women with endometriosis and infertility: a cross-sectional study. BMC Womens Health. 2020; 20(1):124. PMC: 7291762. DOI: 10.1186/s12905-020-00987-7. View

10.

OHara R, Rowe H, Fisher J . Self-management factors associated with quality of life among women with endometriosis: a cross-sectional Australian survey. Hum Reprod. 2020; 36(3):647-655. DOI: 10.1093/humrep/deaa330. View

11.

Vilagut G, Valderas J, Ferrer M, Garin O, Lopez-Garcia E, Alonso J . [Interpretation of SF-36 and SF-12 questionnaires in Spain: physical and mental components]. Med Clin (Barc). 2008; 130(19):726-35. DOI: 10.1157/13121076. View

12.

Rzonca E, Bien A, Wdowiak A, Szymanski R, Iwanowicz-Palus G . Determinants of Quality of Life and Satisfaction with Life in Women with Polycystic Ovary Syndrome. Int J Environ Res Public Health. 2018; 15(2). PMC: 5858445. DOI: 10.3390/ijerph15020376. View

13.

Parra R, Feitosa M, Camargo H, Valerio F, Zanardi J, Rocha J . The impact of laparoscopic surgery on the symptoms and wellbeing of patients with deep infiltrating endometriosis and bowel involvement. J Psychosom Obstet Gynaecol. 2020; 42(1):75-80. DOI: 10.1080/0167482X.2020.1773785. View

14.

Bourdel N, Chauvet P, Billone V, Douridas G, Fauconnier A, Gerbaud L . Systematic review of quality of life measures in patients with endometriosis. PLoS One. 2019; 14(1):e0208464. PMC: 6328109. DOI: 10.1371/journal.pone.0208464. View

15.

Missmer S, Tu F, Agarwal S, Chapron C, Soliman A, Chiuve S . Impact of Endometriosis on Life-Course Potential: A Narrative Review. Int J Gen Med. 2021; 14:9-25. PMC: 7800443. DOI: 10.2147/IJGM.S261139. View

16.

Soliman A, Coyne K, Zaiser E, Castelli-Haley J, Fuldeore M . The burden of endometriosis symptoms on health-related quality of life in women in the United States: a cross-sectional study. J Psychosom Obstet Gynaecol. 2017; 38(4):238-248. DOI: 10.1080/0167482X.2017.1289512. View

17.

De Graaff A, van Lankveld J, Smits L, Van Beek J, Dunselman G . Dyspareunia and depressive symptoms are associated with impaired sexual functioning in women with endometriosis, whereas sexual functioning in their male partners is not affected. Hum Reprod. 2016; 31(11):2577-2586. DOI: 10.1093/humrep/dew215. View

18.

De Graaff A, DHooghe T, Dunselman G, Dirksen C, Hummelshoj L, Simoens S . The significant effect of endometriosis on physical, mental and social wellbeing: results from an international cross-sectional survey. Hum Reprod. 2013; 28(10):2677-85. DOI: 10.1093/humrep/det284. View

19.

Wilhelm K, Finch A, Davenport T, Hickie I . What can alert the general practitioner to people whose common mental health problems are unrecognised?. Med J Aust. 2008; 188(S12):S114-8. DOI: 10.5694/j.1326-5377.2008.tb01873.x. View

20.

Schneider M, Vitonis A, Fadayomi A, Charlton B, Missmer S, DiVasta A . Quality of Life in Adolescent and Young Adult Women With Dyspareunia and Endometriosis. J Adolesc Health. 2020; 67(4):557-561. DOI: 10.1016/j.jadohealth.2020.02.024. View