Association Between Exposure and Suicidal Behavior in Patients Attending Primary Health Care Clinics

Overview

Journal Pathogens

Date 2021 Jun 2

PMID 34070892

Citations 8

Authors

Cosme Alvarado-Esquivel

Sergio Estrada-Martinez

Agar Ramos-Nevarez

Alma Rosa Perez-Alamos

Isabel Beristain-Garcia

Angel Osvaldo Alvarado-Felix

Sandra Margarita Cerrillo-Soto

Antonio Sifuentes-Alvarez

Gustavo Alexis Alvarado-Felix

Carlos Alberto Guido-Arreola

Leandro Saenz-Soto

Affiliations

Soon will be listed here.

Abstract

This study aimed to determine the association between suicidal behavior and seroreactivity in 2045 patients attending primary care clinics. IgG antibodies against were found in 37 (12.1%) out of 306 individuals with a history of suicidal ideation and in 134 (7.7%) of 1739 individuals without this history (OR: 1.64; 95% CI: 1.11-2.42; = 0.01). Seropositivity to was associated with suicidal ideation in women (OR: 1.56; 95% CI: 1.01-2.42; = 0.03) and individuals aged ≤30 years (OR: 3.25; 95% CI: 1.53-6.88; = 0.001). No association between the rates of high (>150 IU/mL) levels of anti- IgG antibodies and suicidal ideation or suicide attempts was found. IgG antibodies against were found in 22 of 185 (11.9%) individuals with a history of suicide attempts and in 149 (8.0%) of 1860 individuals without this history (OR: 1.54; 95% CI: 0.96-2.49; = 0.06). The seroprevalence of infection was associated with suicide attempts in individuals aged 31-50 years (OR: 2.01; 95% CI: 1.09-3.71; = 0.02), and with more than three suicide attempts (OR: 4.02; 95% CI: 1.34-12.03; = 0.008). Our results indicate that exposure is associated with suicidal behavior among patients attending primary care clinics.

Citing Articles

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