Usefulness of International Normalized Ratio to Albumin Ratio for Evaluation of Mortality in Hepatitis B Virus-Associated Decompensated Cirrhosis

Overview

Journal Biomed Res Int

Publisher Wiley

Specialties Biomedical Engineering
Biotechnology
General Medicine

Date 2021 May 31

PMID 34055994

Citations 6

Authors

Ming Cai

Zhong Han

Xia He

Jinfei Zhang

Affiliations

Soon will be listed here.

Abstract

Background: We sought to determine the prognostic value of prothrombin time-international normalized ratio to albumin ratio (PTAR) in patients with hepatitis B virus-associated decompensated cirrhosis (HBV-DeCi).

Methods: The study enrolled 166 HBV-DeCi patients. Multivariate regression analysis was performed to identify predictors associated with mortality.

Results: Among the 166 HBV-DeCi patients, 27 (16.3%) had died by 30 days after admission. PTAR was markedly increased in nonsurvivors compared with survivors, and had a significant positive correlation with disease severity. Multivariate analysis identified PTAR as an effective independent predictor for mortality in HBV-DeCi patients.

Conclusions: High PTAR was associated with poor outcomes and can act as a novel prognostic predictor for mortality in HBV-DeCi patients.

Citing Articles

D-dimer-to-platelet count ratio as a novel indicator for predicting prognosis in HBV-related decompensated cirrhosis.

He X, Ding Q Heliyon. 2024; 10(5):e26585.

PMID: 38434313 PMC: 10907634. DOI: 10.1016/j.heliyon.2024.e26585.

Prognostic value of neutrophil count to albumin ratio in patients with decompensated cirrhosis.

Yao J, Xu X, Gong K, Tu H, Xu Z, Ye S Sci Rep. 2023; 13(1):20759.

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Predictive Value of the Prothrombin Time-International Normalized Ratio to Albumin Ratio in the Prognosis of Patients with Hepatitis B Virus-Related Acute-on-Chronic Liver Failure.

Sheng Y, Zeng Y, Luo W, Zhang X, Wang H, Jiao J Int J Gen Med. 2023; 16:4565-4572.

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Prognostic nutritional index: A potential biomarker for predicting the prognosis of decompensated liver cirrhosis.

Xie Y, He C, Wang W Front Nutr. 2023; 9:1092059.

PMID: 36687701 PMC: 9852856. DOI: 10.3389/fnut.2022.1092059.

International Normalized Ratio-to-Albumin Ratio as a Novel Marker of Upper Gastrointestinal Bleeding Severity.

Choi J, Lee J, Lee S, Kim Y, Lee Y, Kim T Gastroenterol Res Pract. 2022; 2022:1172540.

PMID: 36275426 PMC: 9584709. DOI: 10.1155/2022/1172540.

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