Challenges in Exploring and Manipulating the Human Skin Microbiome

Overview

Journal Microbiome

Publisher Biomed Central

Specialties Genetics
Microbiology

Date 2021 May 31

PMID 34053468

Citations 70

Authors

Manon Boxberger

Valerie Cenizo

Nadim Cassir

Bernard La Scola

Affiliations

Soon will be listed here.

Abstract

The skin is the exterior interface of the human body with the environment. Despite its harsh physical landscape, the skin is colonized by diverse commensal microbes. In this review, we discuss recent insights into skin microbial populations, including their composition and role in health and disease and their modulation by intrinsic and extrinsic factors, with a focus on the pathobiological basis of skin aging. We also describe the most recent tools for investigating the skin microbiota composition and microbe-skin relationships and perspectives regarding the challenges of skin microbiome manipulation. Video abstract.

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