The Effects of Rice Husk Liquid Smoke in Porphyromonas Gingivalis-Induced Periodontitis

Overview

Journal Eur J Dent

Publisher Thieme

Specialty Dentistry

Date 2021 May 27

PMID 34041725

Citations 10

Authors

Theresia Indah Budhy

Ira Arundina

Meircurius Dwi Condro Surboyo

Anisa Nur Halimah

Affiliations

Soon will be listed here.

Abstract

Objectives: The purpose of this study was to analyze the effects of rice husk liquid smoke in -induced periodontitis in the inflammatory and proliferation marker such as nuclear factor kappa β (NF-kB), tumor necrosis factor-α (TNF-α), interleukin-6 (IL-6), transforming growth factor-β (TGF-β), fibroblast growth factor 2 (FGF2), collagen type 1 (COL-1) expression, and the number of macrophages, lymphocytes, and fibroblasts.

Materials And Methods: Rice husk liquid smoke is obtained by the pyrolysis process. -induced periodontitis in 20 μL phosphate-buffered saline containing 1 × 10 CFU was injected into the lower anterior gingival sulcus of Wistar rats. The periodontitis was then treated with 20 μL/20 g body weight of rice husk liquid smoke once a day for 2 and 7 days, respectively. After treatment, the bone and lower anterior gingival sulcus were analyzed with immunohistochemistry and hematoxylin-eosin staining.

Results: The treatment of periodontitis with rice husk liquid smoke showed a lower NF-kB, TNF-α, and IL-6 expression and a higher TGF-β, FGF2, and COL-1 expression than the control after treatment for 2 and 7 days ( < 0.05), respectively. The number of macrophages and fibroblasts was also higher when compared with the control group ( < 0.05), but the number of lymphocytes was lower than the control ( < 0.05).

Conclusion: Rice husk liquid smoke showed its effects on -induced periodontitis with a decrease in inflammatory markers and an increase in proliferation markers. The development of a rice husk liquid smoke periodontitis treatment is promising.

Citing Articles

Phytochemical Profiling and Wound Healing Activity of Liquid Smoke in .

Tarigan D, Tarigan Y, Prakasita V, Prasetyaningsih A, Kachingwe B J Exp Pharmacol. 2024; 16:339-350.

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Nanoparticle-Based Rice Husk Liquid Smoke as Periodontitis Therapy through OPG, RANK, and RANKL Expression.

Arundina I, Budhy T, Oki A, Surboyo M, Santosh A, Sidarningsih Int J Biomater. 2024; 2024:5015893.

PMID: 38912518 PMC: 11192596. DOI: 10.1155/2024/5015893.

The Potential Role of Reactive Oxygen Species Produced by Low-Density Neutrophils in Periodontitis.

Mousa A, Al Hussaini A, Hussein H Eur J Dent. 2024; 18(4):1142-1148.

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6-Octadecenoic and Oleic Acid in Liquid Smoke Rice Husk Showed COVID-19 Inhibitor Properties.

Arundina I, Frimayanti N, Surboyo M, Budhy T, Iskandar B Adv Pharmacol Pharm Sci. 2024; 2024:8105595.

PMID: 38699656 PMC: 11065493. DOI: 10.1155/2024/8105595.

Influence of Bariatric Surgery on Oral Microbiota: A Systematic Review.

Adawi H, Aggarwal A, Jain S, Othman M, Othman A, Zakri R Eur J Dent. 2022; 17(3):602-614.

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