Resolution of Inflammatory Pain by Endogenous Chemerin and G Protein-Coupled Receptor ChemR23

Overview

Journal Neurosci Bull

Specialty Neurology

Date 2021 May 27

PMID 34041712

Citations 4

Authors

Ya-Kai Xie

Hao Luo

Xiao-Yun Qiu

Zhen-Zhong Xu

Affiliations

Soon will be listed here.

Citing Articles

Inflammation in pathogenesis of chronic pain: Foe and friend.

Fang X, Zhai M, Zhu M, He C, Wang H, Wang J Mol Pain. 2023; 19:17448069231178176.

PMID: 37220667 PMC: 10214073. DOI: 10.1177/17448069231178176.

Structure-guided peptide engineering of a positive allosteric modulator targeting the outer pore of TRPV1 for long-lasting analgesia.

Zhang H, Lin J, Xie Y, Song X, Sun J, Zhang B Nat Commun. 2023; 14(1):4.

PMID: 36596769 PMC: 9810691. DOI: 10.1038/s41467-022-34817-1.

Inflammation and Infection in Pain and the Role of GPR37.

Zhang Q, Bang S, Chandra S, Ji R Int J Mol Sci. 2022; 23(22).

PMID: 36430912 PMC: 9692891. DOI: 10.3390/ijms232214426.

Specialized Pro-Resolving Mediators as Resolution Pharmacology for the Control of Pain and Itch.

Ji R Annu Rev Pharmacol Toxicol. 2022; 63:273-293.

PMID: 36100219 PMC: 10290889. DOI: 10.1146/annurev-pharmtox-051921-084047.

References

Arita M, Bianchini F, Aliberti J, Sher A, Chiang N, Hong S . Stereochemical assignment, antiinflammatory properties, and receptor for the omega-3 lipid mediator resolvin E1. J Exp Med. 2005; 201(5):713-22. PMC: 2212834. DOI: 10.1084/jem.20042031. View

Cash J, Christian A, Greaves D . Chemerin peptides promote phagocytosis in a ChemR23- and Syk-dependent manner. J Immunol. 2010; 184(9):5315-24. PMC: 4237835. DOI: 10.4049/jimmunol.0903378. View

Doyle J, Krishnaji S, Zhu G, Xu Z, Heller D, Ji R . Development of a membrane-anchored chemerin receptor agonist as a novel modulator of allergic airway inflammation and neuropathic pain. J Biol Chem. 2014; 289(19):13385-96. PMC: 4036347. DOI: 10.1074/jbc.M113.522680. View

Mosser D, Edwards J . Exploring the full spectrum of macrophage activation. Nat Rev Immunol. 2008; 8(12):958-69. PMC: 2724991. DOI: 10.1038/nri2448. View

Chen O, Donnelly C, Ji R . Regulation of pain by neuro-immune interactions between macrophages and nociceptor sensory neurons. Curr Opin Neurobiol. 2019; 62:17-25. PMC: 7266706. DOI: 10.1016/j.conb.2019.11.006. View

Gisondi P, Lora V, Bonauguri C, Russo A, Lippi G, Girolomoni G . Serum chemerin is increased in patients with chronic plaque psoriasis and normalizes following treatment with infliximab. Br J Dermatol. 2012; 168(4):749-55. DOI: 10.1111/bjd.12118. View

Xu Z, Zhang L, Liu T, Park J, Berta T, Yang R . Resolvins RvE1 and RvD1 attenuate inflammatory pain via central and peripheral actions. Nat Med. 2010; 16(5):592-7, 1p following 597. PMC: 2866054. DOI: 10.1038/nm.2123. View

Huang N, Becker S, Boularan C, Kamenyeva O, Vural A, Hwang I . Canonical and noncanonical g-protein signaling helps coordinate actin dynamics to promote macrophage phagocytosis of zymosan. Mol Cell Biol. 2014; 34(22):4186-99. PMC: 4248717. DOI: 10.1128/MCB.00325-14. View

Bang S, Xie Y, Zhang Z, Wang Z, Xu Z, Ji R . GPR37 regulates macrophage phagocytosis and resolution of inflammatory pain. J Clin Invest. 2018; 128(8):3568-3582. PMC: 6063480. DOI: 10.1172/JCI99888. View

10.

Fang Y, Zhu J, Duan W, Xie Y, Ma C . Inhibition of Muscular Nociceptive Afferents via the Activation of Cutaneous Nociceptors in a Rat Model of Inflammatory Muscle Pain. Neurosci Bull. 2019; 36(1):1-10. PMC: 6940416. DOI: 10.1007/s12264-019-00406-4. View

11.

Serhan C, Petasis N . Resolvins and protectins in inflammation resolution. Chem Rev. 2011; 111(10):5922-43. PMC: 3192290. DOI: 10.1021/cr100396c. View

12.

Ghasemlou N, Chiu I, Julien J, Woolf C . CD11b+Ly6G- myeloid cells mediate mechanical inflammatory pain hypersensitivity. Proc Natl Acad Sci U S A. 2015; 112(49):E6808-17. PMC: 4679057. DOI: 10.1073/pnas.1501372112. View

13.

Park C, Lu N, Xu Z, Liu T, Serhan C, Ji R . Resolving TRPV1- and TNF-α-mediated spinal cord synaptic plasticity and inflammatory pain with neuroprotectin D1. J Neurosci. 2011; 31(42):15072-85. PMC: 3202339. DOI: 10.1523/JNEUROSCI.2443-11.2011. View

14.

Serhan C, Chiang N, Van Dyke T . Resolving inflammation: dual anti-inflammatory and pro-resolution lipid mediators. Nat Rev Immunol. 2008; 8(5):349-61. PMC: 2744593. DOI: 10.1038/nri2294. View

15.

Caterina M, Leffler A, Malmberg A, Martin W, Trafton J, Koltzenburg M . Impaired nociception and pain sensation in mice lacking the capsaicin receptor. Science. 2000; 288(5464):306-13. DOI: 10.1126/science.288.5464.306. View