Preventive Bundle Approach Decreases the Incidence of Ventilator-associated Pneumonia in Newborn Infants

Overview

Journal J Perinatol

Specialty Gynecology & Obstetrics

Date 2021 May 26

PMID 34035449

Citations 4

Authors

Alejandro Pinilla-Gonzalez

Alvaro Solaz-Garcia

Anna Parra-Llorca

Inmaculada Lara-Canton

Ana Gimeno

Isabel Izquierdo

Maximo Vento

Maria Cernada

Affiliations

Soon will be listed here.

Abstract

Objective: We hypothesized that the implementation of evidence-based interventions shaping a bundle approach could significantly reduce the incidence of ventilator-associated pneumonia (VAP) in the neonatal intensive care unit.

Study Design: We conducted a prospective observational cohort study including neonates undergoing mechanical ventilation >48 h. VAP rate and endotracheal intubation ratio were compared before (pre-period) and after (post-period) applying VAP prevention bundle strategies.

Result: One hundred seventy-four neonates were included in pre-period (30 months) and 106 in post-period (17 months). Demographic characteristics were comparable and device use ratios were similar. Twenty-eight VAP episodes were diagnosed, 25 in the first period and 3 after the implementation of prevention bundle. This represents a reduction in the incidence rate from 11.79 to 1.93 episodes/1000 ventilator days (p < 0.01).

Conclusion: The implementation of an educational evidence-based program using a bundle approach to prevent VAP has shown a statistically significant reduction in its incidence density.

Citing Articles

Variations and National Perspectives on Evaluation and Management of Ventilator-Associated Pneumonia in Neonatal Intensive Care Units: An In-Depth Survey Analysis.

Shehzad I, Raju M, Manzar S, Dubrocq G, Sagar M, Vora N Cureus. 2024; 16(7):e64944.

PMID: 39156390 PMC: 11330674. DOI: 10.7759/cureus.64944.

The spectrum of pneumonia among intubated neonates in the neonatal intensive care unit.

Bondarev D, Ryan R, Mukherjee D J Perinatol. 2024; 44(9):1235-1243.

PMID: 38698211 PMC: 11379627. DOI: 10.1038/s41372-024-01973-9.

Ventilator-Associated Pneumonia in the Neonatal Intensive Care Unit-Incidence and Strategies for Prevention.

Rangelova V, Kevorkyan A, Raycheva R, Krasteva M Diagnostics (Basel). 2024; 14(3).

PMID: 38337756 PMC: 10854825. DOI: 10.3390/diagnostics14030240.

Risk factors for neonatal VAP: A retrospective cohort study.

Dang J, He L, Li C Exp Biol Med (Maywood). 2023; 248(23):2473-2480.

PMID: 38159075 PMC: 10903256. DOI: 10.1177/15353702231220673.

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