Tracheobronchial Stents in Patients with Malignant Airway Disease: Finnish Tertiary Care Experience

Overview

Journal Interact Cardiovasc Thorac Surg

Publisher Oxford University Press

Specialties Cardiology & Vascular Diseases
General Surgery
Pulmonary Medicine

Date 2021 May 22

PMID 34021347

Citations 2

Authors

Johannes Routila

Eino Herhi

Jarkko Korpi

Jaakko Pulkkinen

Petri Koivunen

Jami Rekola

Affiliations

Soon will be listed here.

Abstract

Objectives: Tracheobronchial stenting has an established role in the palliation of malignant central airway obstruction (CAO). The purpose of this study is to describe the experience with self-expanding metal airway stents in 2 tertiary referral centres, covering a third of the population of Finland.

Methods: Patients referred to and treated with airway stenting for malignant CAO using self-expanding metal-stents were identified from electronic patient records, and data were collected using a structured Endoscopic Lower Airway Management instrument. Statistical analysis to reveal factors affecting patient benefit and survival was carried out.

Results: A total of 101 patients (mean age 65.8) and 116 procedures were identified. Procedure-related mortality was rare (3/101 patients) and complications infrequent. The median survival was 2.3 months [95% confidence interval (CI): 1.4-3.1). Stent benefit was not significantly affected by clinical characteristics. Survival was impacted by the use of adjunct procedures [hazard ratio (HR) 0.36, 95% CI: 0.23-0.58, P < 0.001), procedural urgency (HR 0.40; 95% CI: 0.23-0.71, P = 0.002) and post-treatment chemoradiotherapy (HR 0.29, 95% CI: 0.15-0.56, P < 0.001).

Conclusions: The beneficial impact observed supports the further use of tracheobronchial stenting in malignant CAO. The use of self-expanding metal stents is encouraged.

Citing Articles

Patient-centred outcome following endoscopic management of benign central airway obstruction.

Bogh M, Larsen D, Lonka M, Schytte S, Pedersen U, Gade S Eur Arch Otorhinolaryngol. 2025; .

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Palliative endoscopic treatment of malignant central airway obstruction.

Bogh M, Heinonen S, Larsen D, Gade S, Schytte S, Pedersen U BMC Pulm Med. 2024; 24(1):635.

PMID: 39734226 PMC: 11684241. DOI: 10.1186/s12890-024-03432-9.

Predictors in the treatment of malignant central airway obstruction with silicone stents.

Bogh M, Gade S, Larsen D, Schytte S, Pedersen U, Kjaergaard T Eur Arch Otorhinolaryngol. 2024; 281(3):1457-1462.

PMID: 38183453 PMC: 10858089. DOI: 10.1007/s00405-023-08365-3.

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