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Cutaneous Manifestations of Infection: A Case Report and Review of the Literature

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Date 2021 May 20
PMID 34012223
Citations 2
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Abstract

A 51 year old man with active follicular lymphoma presented with several days of erythematous skin nodules on all extremities two weeks after a self-limited diarrheal illness. All serum immunoglobulin levels were found to be low. Blood cultures grew The patient was given one week of azithromycin with complete resolution of his skin nodules. The literature of skin manifestations seen in active infection are reviewed. The majority of cases occur in immunocompromised hosts, many with low or no serum immunoglobulin levels. Postulated mechanisms include a lack of secretory IgA in intestinal mucosa predisposing susceptible patients to translocated enteric pathogens however the precise pathogenesis underlying cutaneous manifestations are unknown.

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