Cutaneous Manifestations of Infection: A Case Report and Review of the Literature
Overview
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A 51 year old man with active follicular lymphoma presented with several days of erythematous skin nodules on all extremities two weeks after a self-limited diarrheal illness. All serum immunoglobulin levels were found to be low. Blood cultures grew The patient was given one week of azithromycin with complete resolution of his skin nodules. The literature of skin manifestations seen in active infection are reviewed. The majority of cases occur in immunocompromised hosts, many with low or no serum immunoglobulin levels. Postulated mechanisms include a lack of secretory IgA in intestinal mucosa predisposing susceptible patients to translocated enteric pathogens however the precise pathogenesis underlying cutaneous manifestations are unknown.
pancolitis complicated by toxic megacolon in an immunocompetent host.
Hassan S, Alam S, Syed N, Ismail M BMJ Case Rep. 2025; 15(8).
PMID: 39901401 PMC: 9362769. DOI: 10.1136/bcr-2022-249801.
Nakamura I, Kobayashi T, Fukuzawa M, Komori K, Yamaguchi T IDCases. 2024; 37:e02010.
PMID: 38974503 PMC: 11225700. DOI: 10.1016/j.idcr.2024.e02010.
Diaz-Alberola I, Espuch-Oliver A, Fernandez-Segovia F, Lopez-Nevot M Microorganisms. 2024; 12(6).
PMID: 38930460 PMC: 11205354. DOI: 10.3390/microorganisms12061078.