Central Proteins of Plasma in Response to Low-Level Laser Therapy Involve in Body Hemostasis and Wound Repair

Overview

Journal J Lasers Med Sci

Date 2021 May 17

PMID 33995970

Citations 3

Authors

Babak Arjmand

Reza Vafaee

Mohhamadreza Razzaghi

Mostafa Rezaei-Tavirani

Alireza Ahmadzadeh

Sina Rezaei-Tavirani

Mostafa Hamdieh

Affiliations

Soon will be listed here.

Abstract

Low-level laser therapy (LLLT) is accompanied by protein expression change in the body. There are many efforts to find a clear relationship between the differentially expressed proteins. This study aims to find the central differentiated expressed proteins of plasma after LLLT. Six proteins are extracted from a proteomics study and the network including these query proteins plus 100 first neighbors was constructed. The central proteins were determined based on degree value, betweenness centrality, closeness centrality (CC), and stress (The centrality parameters). Among 106 nodes of the network, 10 proteins were characterized with the most values of degree, betweenness centrality, CC, and stress. These proteins were determined as central proteins in response to LLLT in plasma. Three query proteins, AHSG, FGG, and SERPINA1, plus 7 first neighbors, namely FGA, ALB, KNG1, FN1, APP, TIMP1, and F5, were identified as central proteins which were dysregulated.

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References

Zamanian-Azodi M, Rezaei-Tavirani M, Rahmati-Rad S, Hasanzadeh H, Rezaei Tavirani M, Seyyedi S . Protein-Protein Interaction Network could reveal the relationship between the breast and colon cancer. Gastroenterol Hepatol Bed Bench. 2015; 8(3):215-24. PMC: 4553162. View

Dong W, Qiu C, Gong D, Jiang X, Liu W, Liu W . Proteomics and bioinformatics approaches for the identification of plasma biomarkers to detect Parkinson's disease. Exp Ther Med. 2019; 18(4):2833-2842. PMC: 6755458. DOI: 10.3892/etm.2019.7888. View

Kucerova H, Dostalova T, Himmlova L, Bartova J, Mazanek J . Low-level laser therapy after molar extraction. J Clin Laser Med Surg. 2001; 18(6):309-15. View

Rostami-Nejad M, Rezaei-Tavirani M, Zadeh-Esmaeel M, RezaeiTavirani S, Akbari Z, Esmaeili S . Assessment of Cytokine-Mediated Signaling Pathway Dysregulation in Arm Skin After CO2 Laser Therapy. J Lasers Med Sci. 2019; 10(4):257-263. PMC: 6885903. DOI: 10.15171/jlms.2019.42. View

Sun G, Tuner J . Low-level laser therapy in dentistry. Dent Clin North Am. 2004; 48(4):1061-76, viii. DOI: 10.1016/j.cden.2004.05.004. View

Hanash S . Disease proteomics. Nature. 2003; 422(6928):226-32. DOI: 10.1038/nature01514. View

Kilik R, Bober P, Ropovik I, Benacka R, Genci J, Necas A . Proteomic analysis of plasma proteins after low-level laser therapy in rats. Physiol Res. 2020; 68(Suppl 4):S399-S404. DOI: 10.33549/physiolres.934377. View

Werner T . Bioinformatics applications for pathway analysis of microarray data. Curr Opin Biotechnol. 2008; 19(1):50-4. DOI: 10.1016/j.copbio.2007.11.005. View

Shahrokh S, Razzaghi Z, Mansouri V, Ahmadi N . The Impact of Proteomic Investigations on the Development and Improvement of Skin Laser Therapy: A Review Article. J Lasers Med Sci. 2020; 10(Suppl 1):S90-S95. PMC: 6983869. DOI: 10.15171/jlms.2019.S16. View

10.

Posten W, Wrone D, Dover J, Arndt K, Silapunt S, Alam M . Low-level laser therapy for wound healing: mechanism and efficacy. Dermatol Surg. 2005; 31(3):334-40. DOI: 10.1111/j.1524-4725.2005.31086. View

11.

Huang W, Yu J, Jones J, Carter C, Pierzchalski K, Tudor G . Proteomic Evaluation of the Acute Radiation Syndrome of the Gastrointestinal Tract in a Murine Total-body Irradiation Model. Health Phys. 2019; 116(4):516-528. PMC: 6384135. DOI: 10.1097/HP.0000000000000951. View

12.

Teschendorff A, Banerji C, Severini S, Kuehn R, Sollich P . Increased signaling entropy in cancer requires the scale-free property of protein interaction networks. Sci Rep. 2015; 5:9646. PMC: 4412078. DOI: 10.1038/srep09646. View

13.

Mansouri V, Rezaei-Tavirani M, Zadeh-Esmaeel M, Rezaei-Tavirani S, Razzaghi M, Okhovatian F . Analysis of Laser Therapy Effects on Squamous Cell Carcinoma Patients: A System Biology Study. J Lasers Med Sci. 2020; 10(Suppl 1):S1-S6. PMC: 6983861. DOI: 10.15171/jlms.2019.S1. View

14.

Kim S, Kang Y, Park J, Kim E, Park Y . Effects of low-intensity laser therapy on periodontal tissue remodeling during relapse and retention of orthodontically moved teeth. Lasers Med Sci. 2012; 28(1):325-33. DOI: 10.1007/s10103-012-1146-8. View

15.

Van J, Scholey J, Konvalinka A . Insights into Diabetic Kidney Disease Using Urinary Proteomics and Bioinformatics. J Am Soc Nephrol. 2017; 28(4):1050-1061. PMC: 5373465. DOI: 10.1681/ASN.2016091018. View

16.

He X, Zhang J . Why do hubs tend to be essential in protein networks?. PLoS Genet. 2006; 2(6):e88. PMC: 1473040. DOI: 10.1371/journal.pgen.0020088. View

17.

Hashmi J, Huang Y, Osmani B, Sharma S, Naeser M, Hamblin M . Role of low-level laser therapy in neurorehabilitation. PM R. 2010; 2(12 Suppl 2):S292-305. PMC: 3065857. DOI: 10.1016/j.pmrj.2010.10.013. View

18.

Laukens K, Naulaerts S, Vanden Berghe W . Bioinformatics approaches for the functional interpretation of protein lists: from ontology term enrichment to network analysis. Proteomics. 2014; 15(5-6):981-96. DOI: 10.1002/pmic.201400296. View

19.

Hawkins D, Houreld N, Abrahamse H . Low level laser therapy (LLLT) as an effective therapeutic modality for delayed wound healing. Ann N Y Acad Sci. 2006; 1056:486-93. DOI: 10.1196/annals.1352.040. View

20.

Suzuki S, Garcez A, Reese P, Suzuki H, Ribeiro M, Moon W . Effects of corticopuncture (CP) and low-level laser therapy (LLLT) on the rate of tooth movement and root resorption in rats using micro-CT evaluation. Lasers Med Sci. 2017; 33(4):811-821. DOI: 10.1007/s10103-017-2421-5. View