COVID-19 and Hyperglycemia/diabetes
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In early studies regarding coronavirus disease 2019 (COVID-19), type 2 diabetes mellitus was considered to contribute substantially to the disease's inflammatory response. Subsequently, even hyperglycemia, regardless of insulin resistance or diabetes mellitus, was found to be additionally harmful. Recent studies have shown inflammation of the pancreatic β cells in COVID-19, even leading to new onset diabetes mellitus. We hereby summarize core literature on glycemia and COVID-19, and present implicated pathways and mechanisms.
Zhou Y, Yang Z, Zhang S, Zhang D, Luo H, Zhu D Front Endocrinol (Lausanne). 2025; 16:1467303.
PMID: 40046873 PMC: 11879813. DOI: 10.3389/fendo.2025.1467303.
Impact of Hyponatremia on COVID-19-Related Outcomes: A Retrospective Analysis.
Piza P, de Freitas V, Aguiar-Brito I, Calsolari-Oliveira B, Rangel E Biomedicines. 2024; 12(9).
PMID: 39335510 PMC: 11444129. DOI: 10.3390/biomedicines12091997.
Mechanisms of long COVID and the path toward therapeutics.
Peluso M, Deeks S Cell. 2024; 187(20):5500-5529.
PMID: 39326415 PMC: 11455603. DOI: 10.1016/j.cell.2024.07.054.
Mohamed A, Darraj M, Yassin A, Somaili M, Sayed A, Oraibi O BMC Endocr Disord. 2024; 24(1):197.
PMID: 39304825 PMC: 11414278. DOI: 10.1186/s12902-024-01724-z.
The changing trend of fungal infection in invasive rhinosinusitis in the COVID era.
Garg P, Ranjan V, Avnisha , Hembrom S, Goel S, Malhotra S J Family Med Prim Care. 2024; 13(4):1428-1433.
PMID: 38827671 PMC: 11141948. DOI: 10.4103/jfmpc.jfmpc_871_23.