Translational Research in Pediatric Contrast-enhanced Ultrasound

Overview

Journal Pediatr Radiol

Specialty Pediatrics

Date 2021 May 15

PMID 33991196

Authors

Anush Sridharan

Misun Hwang

Shelby Kutty

M Beth McCarville

Harriet J Paltiel

Maciej Piskunowicz

Sphoorti Shellikeri

Elizabeth Silvestro

George A Taylor

Ryne A Didier

Affiliations

Soon will be listed here.

Abstract

The role of contrast-enhanced ultrasound (CEUS) imaging is being widely explored by various groups for its use in the pediatric population. Clinical implementation of new diagnostic or therapeutic techniques requires extensive and meticulous preclinical testing and evaluation. The impact of CEUS will be determined in part by the extent to which studies are oriented specifically toward a pediatric population. Rather than simply applying principles and techniques used in the adult population, these studies are expected to advance and augment preexisting knowledge with pediatric-specific information. To further develop this imaging modality for use in children, pediatric-focused preclinical research is essential. In this paper we describe the development and implementation of the pediatric-specific preclinical animal and phantom models that are being used to evaluate CEUS with the goal of clinical translation to children.

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