Glycoprotein IIb/IIIa Inhibitors for the Neurointerventionalist

Overview

Journal Interv Neuroradiol

Publisher Sage Publications

Specialty Neurology

Date 2021 May 5

PMID 33947250

Citations 2

Authors

Davide Simonato

Robin J Borchert

Marc-Antoine Labeyrie

Maurizio Fuschi

Lucie Thibault

Hans Henkes

David Fiorella

Benjamin Yq Tan

Leonard Ll Yeo

Hegoda Ld Makalanda

Ken Wong

Pervinder Bhogal

Affiliations

Soon will be listed here.

Abstract

Antiplatelet therapies are commonly used in neurointerventional procedures. However, specific guidelines for their use in these settings is lacking and it can often be difficult to balance the potential risks and benefits of these medications. Considering the continued growth and adoption of neurointerventional procedures, it is crucial to understand the properties of these agents in order to use them safely. Large-scale clinical trials are still needed to clarify many of these aspects for this emerging field. However, the existing literature already provides insight into which antiplatelet drugs are of benefit to the neurointerventionalist as well as their associated risks of ischemic and hemorrhagic complications. Hence, this review focuses on the applications of GPIIb/IIIA inhibitors to neurointerventional procedures.

Citing Articles

Comparison of Safety and Efficacy after Emergency Stenting in Patients Exhibiting Intracranial Atherosclerotic Stenosis Associated with Large-vessel Occlusion with and without Intravenous Infusion of Tirofiban.

Garayzade R, Berlis A, Schiele S, Schneider H, Ertl M, Muller G Cardiovasc Intervent Radiol. 2023; 46(3):377-384.

PMID: 36797426 PMC: 10014670. DOI: 10.1007/s00270-023-03372-7.

P2Y12 inhibitors for the neurointerventionalist.

Borchert R, Simonato D, Hickman C, Fuschi M, Thibault L, Henkes H Interv Neuroradiol. 2021; 28(1):92-103.

PMID: 33947251 PMC: 8905084. DOI: 10.1177/15910199211015042.

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